Consider the estrogen receptor (ER), a cell-cell signaling molecule which can be mutated to caus3 cancer. ER has a very short half life of 30 minutes. Consider a cell that starts out with 20,000 molecules of estrogen receptor at the start of your experiemnt. Ar t=0 you treat the cell. At t=0 you treat the cell with two drugs. 1)alpha-amanitin, a poisonous chemical from mushrooms that inhibits the enzymatic activity of RNA polymerase (this is why you should know your mushrooms) and 2) cycloheximide, a drug that inhibits translation by the ribosome. Under these conditions, how many molecules of ER protein will be present at the following times?
Consider the estrogen receptor (ER), a cell-cell signaling molecule which can be mutated to caus3 cancer. ER has a very short half life of 30 minutes. Consider a cell that starts out with 20,000 molecules of estrogen receptor at the start of your experiemnt. Ar t=0 you treat the cell. At t=0 you treat the cell with two drugs. 1)alpha-amanitin, a poisonous chemical from mushrooms that inhibits the enzymatic activity of RNA polymerase (this is why you should know your mushrooms) and 2) cycloheximide, a drug that inhibits translation by the ribosome. Under these conditions, how many molecules of ER protein will be present at the following times?
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter5: Membranes And Transport
Section: Chapter Questions
Problem 2ITD: Some cancer cells are insensitive to typical chemotherapy. Research into the mechanisms underlying...
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Consider the estrogen receptor (ER), a cell-cell signaling molecule which can be mutated to caus3 cancer. ER has a very short half life of 30 minutes. Consider a cell that starts out with 20,000 molecules of estrogen receptor at the start of your experiemnt. Ar t=0 you treat the cell. At t=0 you treat the cell with two drugs. 1)alpha-amanitin, a poisonous chemical from mushrooms that inhibits the enzymatic activity of RNA polymerase (this is why you should know your mushrooms) and 2) cycloheximide, a drug that inhibits translation by the ribosome. Under these conditions, how many molecules of ER protein will be present at the following times?
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