Question 8 Listen In prostate cancer, several genes are known to be methylated that are not methylated in normal tissue. Based on this, one might expect that ☐ a) In cancer cells, these genes are transcribed more than in normal cells and proteins that stimulate cell division are made. b) In cancer cells, these genes are transcribed less than normal and proteins that inhibit cell division are made c) In cancer cells, these genes are transcribed less than normal and proteins that inhibit cell division are not made. d) In cancer cells, these genes are transcribed less than normal and proteins that stimulate cell division are made.

Question 8 Listen In prostate cancer, several genes are known to be methylated that are not methylated in normal tissue. Based on this, one might expect that ☐ a) In cancer cells, these genes are transcribed more than in normal cells and proteins that stimulate cell division are made. b) In cancer cells, these genes are transcribed less than normal and proteins that inhibit cell division are made c) In cancer cells, these genes are transcribed less than normal and proteins that inhibit cell division are not made. d) In cancer cells, these genes are transcribed less than normal and proteins that stimulate cell division are made.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question 3 Review transcription. Match the term and its description. Each term can only be used once. RNA synthesis is catalyzed by this enzyme called | Choose ) The DNA sequence where RNA polymerase attaches is called | Choose | In bacteria, the sequence signaling the end of transcription is called | Choose J The stretch of DNA that is transcribed is called | Choose | These factors mediate the binding of RNA polymerase and the | Choose initiation of transcription > > >
Question 41 The mechanism of activation of eukaryotic genes involves addition and removal of phosphate residues from some of the transcription factors. (A) True B) False
QUESTION 7 After you graduate, you are working at a laboratory that identifies a novel protein called Leprechaun. To determine in which organelles Leprechaun is found, you decide to express the Leprechaun gene in HeLa cells using a plasmid. Since you have generated an antibody that recognizes an epitope within the Leprechaun protein, which technique will you use to identify its localization within the HeLa cells? OA. SDS-PAGE O B. Immunocytochemistry O C. Western blot OD. Transmission electron microscopy (TEM) OE. Immunohistochemistry QUESTION 8 Which of the following statements regarding electron microscopy is TRUE? OA. White light is utilized to illuminate the sample for imaging in all types of electron microscopy. OB. Electrons pass through the object being examined in transmission electron microscopy (TEM). OC. In scanning electron microscopy (SEM) electrons, electrons bounce off the surface of the sample. OD. Electron microscopy can be used to view structures as small as 2 nm in…
question 26 What is true for CpG Islands: stretches of a few hundred base pairs of DNA where cytosines are unmethylated are not associated with genes are not found around the promoters are associated with silenced genes
Question 9 Both conservative and replicative transposition result in movement of the transposon; however, only conservative transcription Group of answer choices A. Transfers the transposition to the new location without copying it B. Has transposase that cuts at inverted repeats and target sequences C. Produces a second copy of the transposon sequence D. Inserts the transposon sequence into target sequences
Question 5 Review after transcription modification. Match the term and its description. Each term can only be used once. Enzymes in the eukaryotic nucleus modify pre-MRNA before the genetic messages are dispatched to the cytoplasm. This process is | Choose | called The 5' end of pre- MRNA receives a modified nucleotide [ Choose ) Long noncoding regions are called | Choose ) This process removes introns and joins exons, creating an mRNA molecule with a continuous coding sequence | Choose ] These consist of a variety of proteins and several small RNAS that recognize the splice sites [ Choose ) > >
Question 15 Only eukaryotic transcription enzymes will synthesize small nuclear RNA molecules involved in the maturation and processing of other RNAS. (A) True B) False
QUESTION 6 Histone modifying enzymes can be over- or under-expressed in a variety of human diseases and cancers. How would overexpression of histone methyltransferases affect transcription throughout the genome? O transcription could be increased or decreased depending on which amino acids in histone proteins were modified by this enzyme O transcription would be increased O transcription would be decreased O transcription would not be affected QUESTION 7 Eukaryotic genomes contain multiple origins of replication, whereas the E. coli genome contains a single origin of replication. Pick the reason(s) that eukaryotes need multiple replication origins from the list below. O Eukaryotes have large genomes O Eukaryotes have multiple chromosomes O Eukaryotic chromosomes are linear O Eukaryotic DNA is packaged in chromatin O Eukaryotes use both leading-strand and lagging-strand DNA synthesis O Eukaryotes use multiple DNA polymerases QUESTION 8 Describe the role the branch point ribose 2'-OH…
Question 23 All may be RNA polymerase Il promoter constituents EXCEPT: A the core element where general transcription factors (GTFS) bind. B) where silencers bind repressors. response elements or GC box D a TATA box upstream the transcription start site.
[ Choose ] [Choose ) in vitro mutagenesis CRISPR-Cas9 system SNP (single nucleotide polymorphism) RNA interference (RNAI) >
Question 1: The figure shows key components of gene transcription in a eukaryotic cell. Indicate what component (A to E) in the drawing corresponds to each of the following: Enhancers, Promoter Proximal Elements, Basal/General Transcription factor, Transcriptional Activators, Mediator Enhancers_______ Promoter Proximal Elements_________ Basal/General Transcription factor____________ Transcriptional Activators___________ Mediator______________ From the list above which proteins bind to enhancers/regulatory switches? Question 2. What is the role of TFIIH in eukaryotic transcription? How would a mutant of TFIIH that is deficient in kinase activity affect transcription? Answer:
QUESTION 23 You can introduce precise edits into the genome using Crispr/Cas9 and ) A. ligation B. homology directed repair C. T-DNA transformation D. CpG methylation E. nonhomologous end joining