Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Also, In the figure above, what differences in the pattern of cell division can we observe between the regions labeled (1) and (2)?
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- In Xenopus, one of the substrates of mitotic CDKs is the phosphatase Cdc25. When phosphorylated by mitotic CDKs, Cdc25 is activated. What is the substrate of Cdc25? How does this information help to explain the rapid rise in mitotic CDK activity as cells enter mitosis?arrow_forwardWhich of the following does not occur during mitosis? (a) (b) (c) (d) Chromatin condenses and forms chromosomes. Chromosomes move to the equator of the cell. Spindle fibres pull homologous chromosomes to opposite poles of the cell. Two new nuclei are formed that have two full sets of genetic information.arrow_forwardCyclin B and Cdk1 make up MPF which is important to the regulation and initiation of mitosis. : a) True b) Falsearrow_forward
- In the experiment below, you have treated cells with different cancer drugs, stained them with propidium iodide, and analyzed them by flow cytometry. Which of the following histograms illustrates what you would expect to see in the event that the spindle assembly checkpoint is activated (focus on the solid line, the dotted line is normal cell cycle control)? 1. D 2. C 3. A 4.Barrow_forwardOne approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study. The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused. That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so). In contrast, in a second experiment…arrow_forwardWhat are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.arrow_forward
- 2.) One experimental tool used in the biological research and in clinical settings is called Fluorescent Activated Cell Sorting (FACS) or cell cytometry. For example, a cell membrane permeable (or nonpolar) chemical called Hoescht 33342 dye will specifically label DNA. Interpret the graph (Figure 17-4) that illustrates normal cells that have been labeled with Hoescht 33342 dye, and assign which phase(s) of the cell cycle (G1, S, G2, or M) corresponds to the fluorescence intensity. Justify your answers. 1 relative fluorescence per cell Figure 17-4 Analysis of Hoechst 33342 fluorescence in a population of cells sorted in a flow cytometer (Problem 17-15). number of cellsarrow_forwardCan you draw 4th cell division of the adult stem cells. 1st and 2nd are symmetrically. 3rd and 4th are asymmetrically. What kind of cell is the product at the 4th division? Explain your reasoningarrow_forward
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