According to the picture above, the cell shown is going through [Select ] and is in the [Select ] stage of cell division.

The Rb protein has been called the “master brake” of the cell cycle. Describe how the Rb protein acts as a cell cycle brake. How is the brake released in mid- to late G1 to allow the cell to proceed to S phase?

Which phases of the cell cycle is generally the longest in the cells of a mature eukaryote? What steps make it longest phase?

What are the conditions that might cause a cell to halt the cell cycle

Suppose you have a way of measuring the amount of DNA in a single cell during the cell cycle. You first measure the amount at the G1 phase. At what points during the rest of the cell cycle would you predict changes in the amount of DNA per cell?

A researcher, who is examining a sample of cells of the same types at different stages of cell division, isolates a group of cells in the sample that have 1.5 times the amount of DNA as cells at the G1 phase. Which of the following best describes this group of isolated cells? A B с D They are in the M phase of the cell cycle. They are between the G1 and the S phases in the cell cycle. They are in the S phase of the cell cycle. They are in the G2 phase of the cell cycle.

In the experiment below, you have treated cells with different cancer drugs, stained them with propidium iodide, and analyzed them by flow cytometry. Which of the following histograms illustrates what you would expect to see in the event that the spindle assembly checkpoint is activated (focus on the solid line, the dotted line is normal cell cycle control)?       1. D 2. C 3. A 4.B

One approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study.  The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused.  That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so).  In contrast, in a second experiment…

What are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.

Can you draw 4th cell division of the adult stem cells. 1st and 2nd are symmetrically. 3rd and 4th are asymmetrically. What kind of cell is the product at the 4th division? Explain your reasoning