Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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In the experiment below, you have treated cells with different cancer drugs, stained them with propidium iodide, and analyzed them by flow cytometry. Which of the following histograms illustrates what you would expect to see in the event that the spindle assembly checkpoint is activated (focus on the solid line, the dotted line is normal cell cycle control)?
1. D
2. C
3. A
4.B
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- what is the correct answer? During telophase of mitosis: A. dyad chromosomes form B. DNA replicates C. chromosomes line up D. dyad chromosomes divide E. cytokinesis beginsarrow_forwardIf we looked into the nucleus of a normal somatic cell and if we condensed the chromatin, in which phase of the cell cycle would the cell be in for the chromosomes to have this specific structure? a. G0 b. G1 c. S d. G2 e. none of the abovearrow_forwardOne approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study. The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused. That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so). In contrast, in a second experiment…arrow_forward
- 1) Use your knowledge of the cell cycle to explain why onion root tip cells spend most of their time in this stage 2) complete table below of stages and reasoningarrow_forward2.) One experimental tool used in the biological research and in clinical settings is called Fluorescent Activated Cell Sorting (FACS) or cell cytometry. For example, a cell membrane permeable (or nonpolar) chemical called Hoescht 33342 dye will specifically label DNA. Interpret the graph (Figure 17-4) that illustrates normal cells that have been labeled with Hoescht 33342 dye, and assign which phase(s) of the cell cycle (G1, S, G2, or M) corresponds to the fluorescence intensity. Justify your answers. 1 relative fluorescence per cell Figure 17-4 Analysis of Hoechst 33342 fluorescence in a population of cells sorted in a flow cytometer (Problem 17-15). number of cellsarrow_forwardA cell stops proliferating when treated with a chemical analog to fucoxanthin. When these cells are analyzed and compared to untreated cells according to the amount of DNA they contain using flow cytometry, the graphs in the figure below are obtained. Which of the following answers would NOT cause this result?arrow_forward
- Oncologists (cancer doctors) frequently measure the mitotic index of tumor cells when they are removed via surgery or biopsy. What do you think is the value of finding out the mitotic index of these cells?arrow_forwardStarting with one cell, how many cells will be present at the end of mitosis? Group of answer choices A. 1 B. 0 C. 2 D. 6 E. 4arrow_forwardCan you draw 4th cell division of the adult stem cells. 1st and 2nd are symmetrically. 3rd and 4th are asymmetrically. What kind of cell is the product at the 4th division? Explain your reasoningarrow_forward
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