low pH. Trying to understand how this is controlled, you look for mutants that disrupt the regulation. You find one that is in a completely different gene on a different chromosome? This second gene produces a protein but in the mutant, the protein isn't made and low pH no longer stimulates the transcription of the first gene. What is an explanation for how the second gene is linked to the regulation of the first? Explain your reasoning.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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You are studying the expression of a eukaryotic gene. The gene product is not produced unless the
cell is exposed to a pH of less than 6.0, so you can consider the gene product to be inducible by
low pH. Trying to understand how this is controlled, you look for mutants that disrupt the
regulation. You find one that is in a completely different gene on a different chromosome? This
second gene produces a protein but in the mutant, the protein isn't made and low pH no longer
stimulates the transcription of the first gene. What is an explanation for how the second gene is
linked to the regulation of the first? Explain your reasoning.
Transcribed Image Text:You are studying the expression of a eukaryotic gene. The gene product is not produced unless the cell is exposed to a pH of less than 6.0, so you can consider the gene product to be inducible by low pH. Trying to understand how this is controlled, you look for mutants that disrupt the regulation. You find one that is in a completely different gene on a different chromosome? This second gene produces a protein but in the mutant, the protein isn't made and low pH no longer stimulates the transcription of the first gene. What is an explanation for how the second gene is linked to the regulation of the first? Explain your reasoning.
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