[Ligand] (µM) Fractional saturation, Y 1 0.20 0.36 4 0.54 0.62 8 0.70

Aquaculture Science
3rd Edition
ISBN:9781133558347
Author:Parker
Publisher:Parker
Chapter15: Recirculating Systems
Section: Chapter Questions
Problem 3E
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Estimate the binding affi nity of a ligand for its receptor from the following
data: 

[Ligand] (µM)
Fractional saturation, Y
1
0.20
0.36
4
0.54
0.62
8
0.70
Transcribed Image Text:[Ligand] (µM) Fractional saturation, Y 1 0.20 0.36 4 0.54 0.62 8 0.70
Expert Solution
Introduction

The receptor is a protein that is found on the cell surface. These receptors bind to the ligand with a high degree of specificity, based on the structure. Once the ligand binds with the receptor, it induces conformational changes, that allow the initiation of signal transduction. The signaling of hormones, enzymes are mediated by the interaction with the specific receptors.

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