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In an experimental motile fibroblast cell line, Nucleation Promoting Factor (NPF) was mutated in such a way that it no longer could bind to the G-actin monomers. Which of the following would you observe in these cells as a consequence of the mutation at the molecular level? None of the other is true. The cell will not be able to form branching of the actins using Arp2/3 complex at the leading edge and causing movement arrest The filamin protein will not be recruited for crosslinking the actins and will cause the arrest of movement. The Arp2/3 and filamin will not be able to dissociate from actin in the absence of NPF and the cells will be restricted to move in one direction only

In an experimental motile fibroblast cell line, Nucleation Promoting Factor (NPF) was mutated in such a way that it no longer could bind to the G-actin monomers. Which of the following would you observe in these cells as a consequence of the mutation at the molecular level? None of the other is true. The cell will not be able to form branching of the actins using Arp2/3 complex at the leading edge and causing movement arrest The filamin protein will not be recruited for crosslinking the actins and will cause the arrest of movement. The Arp2/3 and filamin will not be able to dissociate from actin in the absence of NPF and the cells will be restricted to move in one direction only

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In an experimental motile fibroblast cell line, Nucleation Promoting Factor (NPF) was mutated in such a way that it no longer could bind to the G-actin monomers. Which of the following would you observe in these cells as a consequence of the mutation at the molecular level? None of the other is true. The cell will not be able to form branching of the actins using Arp2/3 complex at the leading edge and causing movement arrest The filamin protein will not be recruited for crosslinking the actins and will cause the arrest of movement. The Arp2/3 and filamin will not be able to dissociate from actin in the absence of NPF and the cells will be restricted to move in one direction only
Transcribed Image Text:In an experimental motile fibroblast cell line, Nucleation Promoting Factor (NPF) was mutated in such a way that it no longer could bind to the G-actin monomers. Which of the following would you observe in these cells as a consequence of the mutation at the molecular level? None of the other is true. The cell will not be able to form branching of the actins using Arp2/3 complex at the leading edge and causing movement arrest The filamin protein will not be recruited for crosslinking the actins and will cause the arrest of movement. The Arp2/3 and filamin will not be able to dissociate from actin in the absence of NPF and the cells will be restricted to move in one direction only
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