House mouse (Mus musculus) Gene of interest: B4galnt2 (encodes glycosyltransferase enzyme) Allele R: Associated with prolonged bleeding due to issues with blood clotting; associated with resistance to bacterial infections due to absence of intestinal expression. Allele C: Associated with increased susceptibility to bacterial infections; not associated with prolonged bleeding. A B с The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. The population is closed; there are no new mice coming in. The cages are setup to allow for random mating. The B4galnt2 gene is not associated with any mating preferences or non-random mating patterns. Studies have shown that mutations in this locus are Studies have shown that mutations in this locus are extremely rare. The population is EXTREMELY large. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication extremely rare. The population is kept in well maintained environment, free of bacterial infections. The mouse food is supplemented with a low dose of blood coagulator, which helps the blood clot and eliminates any prolonged bleeding. None of the genotypes display any side effects to this medication

1a) In a very large population, if the forward and reverse mutation rates are exactly the same, how would you expect the frequency of an original, non-mutated allele to change in the population over time? Will the population eventually achieve an equilibrium value of the frequency of the non-mutated allele? b) What if the forward mutation rate is one order of magnitude larger (e. 10X) than the reverse mutation rate? Do you expect the frequency of the original, non-mutated allele to increase, decrease, or stay the same over time?  c) If the population size is considerably smaller, does this change your expectations for changes in the frequency of the original, non-mutated allele over several generations?

In a population of 500 fruit flies, 250 are genotype RR, 100 are genotype Rr and 150 are genotype rr. Determine the allele frequencies for this gene in this population. Remember that the frequencies should add to 1. Please show your work.

a) Suppose the frequency of the recessive allele a for the recessive condition albinism is 0.2 Assume the Hardy-Weinberg distribution.    ai) What is the frequency of albinism in the general population?  aii) What fraction of the population are carriers?  b) In a large population of mice, 0.58 have the recessive genetic condition rsiancer (fictional).  Assume the Hardy-Weinberg distribution. What fraction of mice are carriers? Giver your answer with two digits parts the decimal point. c) In a large population of squirrels,  0.14 have the recessive genetic condition nlourianfilindr (fictional).  Assume the Hardy-Weinberg distribution.  What is the frequency of the dominant allele in this population? Give your answer with two digits parts the decimal point. d) In a large population of chimpanzees,  there is a recessive genetic condition telactalase (fictional).  Assume the Hardy-Weinberg distribution.  If the frequency of dominant allele is 0.77 then what fraction of the population has…