2). What is the maximum frequency of recombinant gametes? Illustrate this in an F1 individual with 2 chromosomes, heterozygous for 2 linked genes, with a single cross-over during Meiosis.
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- An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B ● C D E F G, A B • C D V W X, R S •T U E F G, R S•T U V W Xa. Draw the pairing arrangement of these chromosomes in prophase 1 of meiosis. Mention their gametic composition. b. Draw the alternate, adjacent I, and adjacent II segregation patterns in anaphase I of meiosis. Mention their gametic composition.Diagram A represents a chromosomal inversion event. A, B, C, D, E, F, are chromosomal loci. Represents a centromere. Diagram B shows a crossing over event between non-sister chromatids of a non-inverted and an inverted chromosome (darker vs. lighter lines) during meiosis I. Which of the following represents a recombinant chromosome resulting from the cross-over event shown in diagram B? А А в с D E MARK ALL THE ANSWES THAT APPLY. Inversion E B F B B EEEE B F F E в F A E D D с в А F В в F A E D в АAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X a. Draw the pairing arrangement of these chromosomes in prophase I of meiosis. b. Diagram the alternate, adjacent-1, and adjacent-2 segregation patterns in anaphase I of meiosis. c. Give the products that result from alternate, adjacent-1, and adjacent-2 segregation.
- A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. List all the different types of gametes that might be produced by the man.A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman?We have discussed meiosis in yeast. One ascus e one melotic event. Two haploid yeast strains are crossed together, one wild type, the other mutant for 2 linked genes. The resulting diploid strain undergoes melosis eventually (=many meiotic events > many asci). A. What will the results be if the 2 genes are very far away from each other (certainly more than 50 map units)? B. What will the results be if the two genes are right next to each other, "no distance at all, zero distance"? (Explain your answers). Results here are patterns of asci and their percentages. Like for example "50% tetratypes, 0% ditypes", etc. If you forgot what a ditype or a tetratype is, you can illustrate them like that.
- 1. Let's take the example of the gray kangaroo (Macropus fuliginosus) whose ploidy is 8 and the sexual determinism of this species is carried out according to the XY mode. From a male kangaroo: a) Draw the karyotype of this individual, obtained by stopping division at metaphase. Your drawing should include: a. All maternal and paternal chromosomes involved (different colors) b. An example of autosome and heterochromosome c. An example of homologous chromosome, sister chromatid and centromere. d. The total number of chromosomes in a metaphase kangaroo cell. e. A sentence to explain the difference between the terms gene and allele that might apply to this species.A diploid (2n) trihybrid individual with the genotype AaBbDd can make eight genetically different gametes. 2n = 4 n = 2 (1) A d. ID 1 1 2 2 Gt: AaBbDd Loci A/a and D/d are on chromosome 1 and locus B/b is on chromosome 2. Explain how a gamete containing the alleles A, D and b may be produced by meiosis. Refer specifically to meiotic events occurring during Prophase I, Metaphase I, Anaphase I and Anaphase II. (NB: remember to refer to the organism above). CO6) The plant Haplepoppus gracilis is diploid (2n = 4). Inside each cell (represented here by the oval) there are four total chromosomes: one long pair (represented by "A" and "a") and one short pair (represented by "B" and “b"). The following diagrams represent possible anaphases of this cell during meiosis or mitosis. The lines represent chromosomes/chromatids being pulled to either the north or south pole of the cell, and the vertex of each "V" represent the centromere which would be attached to kinetochore microtubules. For representative cells 1– 12, say if the diagram represents a cell in anaphase I of meiosis I, anaphase II of meiosis II, anaphase of mitosis, or shows an impossible situation. If the situation is impossible, explain why. い。 VA Vb VA VB VV. V b Va VB VAVA Vo VB ^^ ^ が VaVA Vo VB くs
- If these segregation patterns are equally likely, what is the probability that a gamete produced by the individual who carries the translocatedchromosome will result in a viable offspring with a normal phenotype?a) Explain why when a chiasma is formed, only 50% of the meiotic products will be of recombinant type. b) Determine the sequence of the three genes (y, cl and vg) that are linked on a chromosome based on the genetic distances provided below: y- vg 43 y- cl vg – cl 5 38A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?
