Histamine is a chemical substance released in inflammatory and allergic response. The histamine H1 receptor is a G protein-coupled receptor that activates phospholipase C in response to the binding of histamine. Arrange the data below showing the process of histamine signal transduction from the H1 receptor. Calcium ions flow through ligand-gated ion channel. Phosphorylation cascade leads to the activation of a cellular response. Calcioum ions activate a protein, leading to a cellular response. Enzyme cleaves PIP2, forming DAG and IP3. Calcium iom concentration increases in the cytosol. IP3 binds to a ligand-gated ion channel in thw ER membrane.

Histamine is a chemical substance released in inflammatory and allergic response. The histamine H1 receptor is a G protein-coupled receptor that activates phospholipase C in response to the binding of histamine. Arrange the data below showing the process of histamine signal transduction from the H1 receptor. Calcium ions flow through ligand-gated ion channel. Phosphorylation cascade leads to the activation of a cellular response. Calcioum ions activate a protein, leading to a cellular response. Enzyme cleaves PIP2, forming DAG and IP3. Calcium iom concentration increases in the cytosol. IP3 binds to a ligand-gated ion channel in thw ER membrane.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section4.5: Intercellular Communication And Signal Transduction

Problem 3CYU: Outline the three general means by which binding of a water soluble extracellular chemical messenger...

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