Compare three types of signaling molecules: neurotransmitters, hormones, and local regulators.

1a) Create a diagram which illustrates the typical signaling mechanism of action G protein-coupled receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can for a novel pathway.

What is the sequence of events that takes place in cell signaling?

Compare and contrast the receptors and signalling cascade, and the physiological roles for two neurotransmitters in the brain   Give examples

Pane Create a diagram which illustrates the typical signalling mechanism of action of g protein coupled and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway. Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? Key What are the physiological processes involved? Is this autocrine, physiological paracrine or endocrine or some combination of them? What is the pathology of the receptor? process involved What are the downstream actions of the receptor? Which molecules does it…

Define cell signaling and outline the five types of cell signaling mechanisms that participate in the regulation of homeostasis and cellular adaptation.

Intracellular signaling pathways provide multiple opportunities for the amplification of a response to an extracellular signal. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a True False

Proteases are enzymes that destroy proteins. Application of these enzymes to an intact cell strips the proteins off the cell surface. If a specific signaling molecule is added to cells stripped of surface proteins and the cell still responds, what must be true of the signaling pathway? The receptor is a ligand-gated ion channel. The signaling molecule doesn't need a receptor. The signal can directly activate the second messenger system and does not need to activate the receptor. The receptor for this signal is inside the cell, and the signaling molecule is nonpolar and can diffuse into the cell.

Describe three types of responses that cells make to signaling molecules.

In terms of cell communication, compare and contrast the action of hydrophilic versus hydrophobic ligands (signaling molecules). What type of receptor is used by these ligands? How does each type of ligand influence cell activity?