Genes that encode proteins that promote apoptosis in response to cellular stress are referred to as: Question 6 options: Tumor suppressors Proto-oncogenes
Q: 8 From the Hill Plot below, the of the first binding event for the receptor-ligand system under…
A: The hill plot is a graph drawn based on the Hill equation given below.This identifies with the…
Q: Why is 1, 2, 3, 4-tetraphenylcylopentadienone a dark purple color while most other organic compounds…
A: Option a: This option is incorrect because, 1, 2, 3, 4 - tetraphenylcylopentadienone is not a…
Q: Predict the product of the following organic reaction: CH₂ CH Ni + 3 H₂ P CH2 Specifically, in the…
A:
Q: Your lunch meal contains rice, fish, vegetables and water for drinks. Identify the nutrients…
A:
Q: STEM Workplace Practices Q5
A: The statement is false. Analytical methods are not assessed only once in their lifecycle for…
Q: __________ is never involved in the initiation of eukaryotic transcription. Question 4 options:…
A: The answer is sigma factor.Explanation:All of the factors have something to do with initiation of…
Q: 2. The mature form of TEM-1 ß-lactamase, an enzyme of 290 amino acid residues that hydrolyzes…
A: Before calculating the isoelectric point (pI) of the enzyme, we need to be thorough with the…
Q: The authors in the abstract given above describe the mechanism for the activation of metallothionein…
A: Many heavy metals are toxic to humans. Certain proteins (like metallothionein) have the ability to…
Q: What is the major organic product of the following sequence of reactions? CN Δ H2 (3 atm) Pt 1.…
A: In the first step Diels alder reaction occurs , then the hydrogenation of double bond occurs where…
Q: I have glucoseoxidase 1000 Udl-1. What is the exact unit of the enzyme that could work for 1…
A: Specific activity of glucose oxidase (from literature) : 200 units/mg protein Calculation: First,…
Q: Complete the following reaction by filling in the necessary reagents. NH₂ S. 1) Br 2) Draw the…
A: Step 1:• In this reaction firstly, amine group undergoes diazotization and further undergoes attack…
Q: using results for experiment below conduct 1 graph of the different factors vs rate of enzyme…
A: The objective of this question is to understand the role of different factors in enzyme activity and…
Q: p53 is an activator of a miRNA called miR-145. miR-145 targets c-myc, a gene that promotes cellular…
A: Increased proliferation and survival.Explanation:Increased proliferation and survival would be the…
Q: A partial diploid in E. coli is created so that LacI is no longer expressed from the genome and is…
A: Partial diploid E.coli has both chromosomal DNA (i.e. genome) and plasmid DNA, but all the genes are…
Q: The student advises using the same selection procedures and inoculating a 5 mL overnight culture…
A: Quantification: The process of plating on agar plates enables the counting of individual colonies,…
Q: pless dont proved hand ratting solution
A: Step 1:The compound is written in Newman Projection. The circle indicates that it is projected in…
Q: Fill in the RNA quantification table below: Sample A260 A280 A260 A280 Concentration (ng/μl)…
A: The conversion factor depends on the type of RNA being quantified.Conversion factors for different…
Q: . An acetate/acetic acid (pKa=4.75) buffer of 500 mL includes 0.1 mol of acetate and 0.5 mol of…
A: The objective of the question is to calculate the volume of 2.0 M NaOH that was added to the buffer…
Q: QUESTION 1 You have a crude lysate sample (CL) containing a mixture of six proteins (1, 2, 3, 4, 5,…
A: Proteins fold in a way where the hydrophobic residues are sequestered towards the interior of the…
Q: Consider the reaction below to answer the following question(s): + HBr A B Br с + D Br Enter the…
A: The kinetically controlled product is DOption 1 is correctExplanation:
Q: Only 500% sure experts solve it correct
A: Peptides and Amino AcidsAmino acid monomers are joined into small chains called peptides by peptide…
Q: 45. A 5-year-old girl with a history of recurrent infections since the age of 4 months is brought to…
A: The objective of the question is to identify the immune system component that is most likely…
Q: phosphofructokinase reaction of Fructose-2,6-bisphosphate is a regulator of both glycolysis and…
A: Step 1:Step 2:Step 3:
Q: pH of solution 14.00 12.00 10.00 8.00- 6.00 First equivalence 4.00 point 2.00- 0 Second equivalence…
A: The given pH value is 7.5 which lie at the Second Titration.The transition region between the…
Q: A drawing of a cell in anaphase is provided. The cell contains 8 unreplicated chromosomes with…
A: Self explanatoryHope the answer was helpful. If any doubts feel free to ask for further…
Q: ẞ-Calendic acid is an omega-6, conjugated fatty acid that is the all-trans isomer of a-calendic…
A: Polyunsaturated fatty acids (PUFA) are fatty acids with more than one double bond. Complete…
Q: How will the information required to describe your RFP be obtained? Which kinds of methods are you…
A: Step 1: Document Analysis:The lab introduction provided is a crucial source of information. By…
Q: You need to make a protein buffer of: 100 mM NaCl ⚫ 25 mM Tris 8 • • 5% w/v glycerol 2 mM DTT Your…
A: In order to calculate how much of each component we should use to get the required buffer, we need…
Q: What is the correct assignment of the names of the functional groups in the following nitrogen-…
A: Step 1:Structure 1:Contains imine functional group. Characteristics of imine functional group are…
Q: The following data is for the oxidation of catechol (the substrate) to o-quinone by the enzyme…
A: Phenoloxidase is a key enzyme in melanization that catalyzes the oxidation of phenols.…
Q: The oxyanion hole of a serine protease has which of the following roles (select all correct…
A: The objective of the question is to identify the roles of the oxyanion hole in a serine protease.…
Q: are best suited for diagnosing a disorder that is caused by low protein expression due to unwanted…
A: Molecular tests are best suited for diagnosing a disorder caused by low protein expression due to…
Q: What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all…
A: Here's a breakdown of why these are not used in the second round: Acetyl-CoA ACP Transacylase: This…
Q: What is the net yield of ATP when 2 molecules of pyruvate are completely oxidized? (enter numerical…
A: The net yield when 2 molecules of pyruvate are completely oxidized is 20 ATP. When 2 molecules of…
Q: Extension Questions Which of the following sequences correctly represents the flow of electrons…
A: Extension questions •The correct sequence representing the flow of electrons during photosynthesis…
Q: You will have to dilute your inital Lysozyme stock in order to pipet volumes larger than 10 uL for…
A: Step 1:For the Bradford assay, the typical concentration range of protein you want to target is…
Q: what is balanced chemical equation for the oxidation of benzoin to benzil using sodium hypochlorite
A: ### Reactants1. **Benzoin**: This is an organic compound with two aromatic rings bonded together…
Q: using sample prep aka the protocol use it to fill in the tables
A: Explanation: Lysozyme (mL): The amount of lysozyme diluted and added to each conical tube. The…
Q: Please help me fill in all the information
A: In order to finish your diagram, you would have to: Assign the proper labels to Complexes I, II (if…
Q: what are three main categories of membrane proteins, and how are they distinguished experimentally?
A: The objective of this question is to identify the three main categories of membrane proteins and…
Q: Draw the major organic product of the following reaction. H CH3CHI (excess) Draw the structure of…
A:
Q: Choose the statement that best explains WHY the aldol condensation is considered base-catalyzed. a…
A: Step 1: Step 2: Step 3: Step 4:
Q: A nonsense mutation results in an exon junction complex remaining on the mRNA. This mRNA:…
A: A nonsense mutation results in an exon junction complex remaining on the mRNA. This mRNA: Will be…
Q: 4. RNA hydrolysis As discussed in class, we can predict how much of RNA we expect to be in a…
A: RNA can undergo slow, nonenzymatic, spontaneous hydrolysis, due to the presence of 2'OH in its…
Q: (5) s) Consider the equation for enzyme action below: E-S E-P E+S complex E+P complex Briefly…
A: Catalyst are chemical compounds that speed up chemical reactions but do not undergo any changes…
Q: Describe in detail what is meant by a "self- restricted/ self-tolerant" T cell. A diagram is…
A: Approach to solving the question:
Q: A particular reaction has a ΔG‡ of 30.0 kJ mol-1 at 25.0 °C. In the presence of an enzyme, the same…
A: Step 1:
Q: Many studies have linked plasmids to bacterial resistance to antibiotics. Closured circular…
A: Focusing on plasmids as a target to combat antibiotic resistance holds promise but requires a…
Q: No hand writingPlease draw out a mechanism thank you so much!
A: Step 1: Step 2: Step 3: Step 4:
Q: Answer the following questions concerning sulfathiazole below by filling ieach blank with the…
A: Step 1: In sulfathiazole, the nitrogen atom is indeed sp² hybridized. This means that one of the…
Question 6 options:
|
|
Tumor suppressors
|
|
|
Proto-oncogenes
|
Step by step
Solved in 2 steps
- Carcinogens generate mutations in: Question 17 options: anti-oncogenes and tumor activation genes proto-oncogenes and tumor suppressor genes proto-oncogenes and tumor activation genes anti-oncogenes and tumor suppressor genesThe Human papillomavirus (HPV) has been linked to an increased risk of cervical cancer. The HPV E6 and E7 proteins govern the cell via altering cellular proteins. The E6 protein interacts with the tumor suppressor protein p53 and directs its ubiquitin-mediated destruction. Can you elaborate about the P63 gene: its function and if it can be altered/mutated by HPV? If it does, what is the relationship between P53 and P63? Thank you!For the normal cell to become a cancer cell, mutations should take place in protooncogenes to become oncogenes as well as mutations in tumor supressor genes to be come mutated tumor supressor genes. Select one: True False
- Match each definition with the corresponding term concerning genes involved in tumor formation. Proto-oncogenes Oncogenes Tumor suppressor genes Haploinsufficiency Answer Bank a gene whose function drives uncontrolled cell division and tumorigenesis a gene regulating cell division that can be mutated into a tumorigenic form a gene that protects a cell from progressing toward cancer a condition in which a single copy of a gene fails to produce enough gene product for normal functionAnswer each question with a paragraph; 3-5 sentences each. Explain the difference between a proto-oncogene and a tumor-suppressor gene. Explain the difference between prokaryotic and eukaryotic cell division. Explain the difference between positive regulation of the cell cycle and negative regulation of the cell cycle. Explain the difference between normal p53 and mutated p53. Find two differences and two similarities between binary fission and mitosis.Why is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene (limit 3-4 sentences)?
- What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53 functions?The C-myc gene is a proto-oncogene which is highly expressed in breast tissue and appears to cause proliferation of breast tissue and its elevated expression is associated with breast cancer. Based just on the ChIP data from the previous questions (also shown below), which of the three drugs (estrogen, tamoxifen and raloxifene) would you recommend for treating breast cancer? Justify your response and explain the potential side effects of each drug.Determine if the gene on the left is a proto-oncogene or tumor suppressor. APC p53 Ras [Choose] [Choose] Tumor suppressor Proto-oncogene [Choose]
- There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes, and DNA stability/repair genes. Define each of these categories and indicate which one you think the RB1 gene belongs to and why.Discuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components (i.e. the proteins associated with cellular checkpoints) of the cell cycle. Tumor growth results when the cell cycle checkpoints are ignored. Give an example of how tumor growth could result from either a loss-of-function or a gain-of-function mutation.What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to cancer?
