45. A 5-year-old girl with a history of recurrent infections since the age of 4 months is brought to the physician for a follow-up examination. She has had multiple episodes of pneumonia, sinusitis, otitis media, and diarrhea. She is at the 20th percentile for height and weight. Her temperature is 37.4°C (99.3°F). Mild crackles are heard bilaterally over the lower lung lobes. Laboratory studies show: Leukocyte count Segmented neutrophils Eosinophils 10,500/mm³ (N=5500-15,500) 57% 2% Lymphocytes 34% CD3+ T lymphocytes 67% CD19+ B lymphocytes 28% CD56+ natural killer cells 5% Monocytes 7% Serum IgA IgG IgM undetectable (N=14-159 mg/dL) 25 mg/dL (N=345-1236) 410 mg/dL (N=43-207) This patient most likely has an abnormality of which of the following immune system components? A) Activation-induced deaminase B) CD40 ligand OC) Class II MHC protein D) Common y chain of the interleukin-2 (IL-2) receptor E) Recombination-activating gene 1 F) Terminal complement

45. A 5-year-old girl with a history of recurrent infections since the age of 4 months is brought to the physician for a follow-up examination. She has had multiple episodes of pneumonia, sinusitis, otitis media, and diarrhea. She is at the 20th percentile for height and weight. Her temperature is 37.4°C (99.3°F). Mild crackles are heard bilaterally over the lower lung lobes. Laboratory studies show: Leukocyte count Segmented neutrophils Eosinophils 10,500/mm³ (N=5500-15,500) 57% 2% Lymphocytes 34% CD3+ T lymphocytes 67% CD19+ B lymphocytes 28% CD56+ natural killer cells 5% Monocytes 7% Serum IgA IgG IgM undetectable (N=14-159 mg/dL) 25 mg/dL (N=345-1236) 410 mg/dL (N=43-207) This patient most likely has an abnormality of which of the following immune system components? A) Activation-induced deaminase B) CD40 ligand OC) Class II MHC protein D) Common y chain of the interleukin-2 (IL-2) receptor E) Recombination-activating gene 1 F) Terminal complement

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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