Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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During DNA replication, DNA methylation:

please explain answer 
a. A and C
b.  B. marks the strand not cut in mismatch repair
c.  A and B
d. A. marks the parental DNA strand
e. C. marks the strand cut in mismatch repair
Expert Solution
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DNA METHYLATION

DNA methylation maintenance occurs in the context of chromatin replication. DNA methylation maintenance is coupled in space and time with DNA replication, which itself occurs on a chromatinized DNA template. The chromatin template, however, poses a specific challenge during replication.

DNA methylation is essential for silencing retroviral elements, regulating tissue-specific gene expression, genomic imprinting, and X chromosome inactivation.

DNA methylation promotes transcription, and histone acetylation reduces transcription.

 

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