Xeroderma pigmentosa (XP): A. is caused by a defect in the mismatch repair system. B. typically results in base substitution mutations. C. can be caused by defects in any of a number of different genes that have to do with DNA repair. D. results when an individual does not spend enough time outside. E. Can be corrected by a direct repair mechanism

Q: mutations

A: Change in a DNA sequence and change in a phenotype or genotype of an organism is called mutation.

Q: Genes with highly similar sequence are often located adjacent one another in the genome. Gene…

A: Gene mutations are changes in single DNA bases, or small intragenic deletions and rearrangements. It…

Q: a way in which proto-oncogenes can change to become genes that induce cancer?

A: A proto-oncogene is a normal gene that can turn into an oncogene due to mutations or increased…

Q: Expansion of a CAG repeat region by 1 repeat is an example of a frameshift mutation. Both DNA…

A: Frameshift mutation: It is a kind of genetic disorder that occurs due to insertion or deletion of…

Q: What are examples of the cells and tissues involved in both repair processes.

A: TISSUE REPAIR PROCESS:- Wound healing completes in three steps:- 1)First Phase:-Hemostasis- This is…

Q: Cystic Fibrosis is caused by a mutation in the CFTR gene, and an ideal form of treatment would be to…

A: Cystic fibrosis is an inherited life threatening disorder that causes severe damages to lungs,…

Q: Explain why harmful mutations tend to disappear, while beneficial mutations become widespread.

A: Mutation can be defined as a heritable genetic change in the genetic material of an organism that…

Q: A genetic researcher notices that individuals with a particular genetic disease have a shortened…

A: Silent Mutation : As the name says silent mutation, these are the mutations in DNA which doesn't…

Q: Double-stranded breaks are repaired by: a). direct reversal of DNA damage b). recombinational repair…

A: Ionizing radiation and radio-mimetic compounds induce DNA double-strand breaks (DSBs), but they may…

Q: Which statement(s) below regarding DNA mutations is true: A. Mutations only occur in genes B.…

A: Ans: D) Mutation can occur in promoters.   Mutation is a change in the sequence of DNA due to…

Q: At birth a child has got blue eyes, but now his/her eyes turn brown. Which of the following…

A: The genes which encode for the eye color actually just decide the levels of pigment to be present in…

Q: Explain point  mutations and frameshift mutations. Which is more apt to disrupt the  structure and…

A: Proteins are the expression of the information present in the DNA (deoxyribonucleic acid). This…

Q: SCENARIO: You are studying a disease caused when the gene called BMP5 is not transcribed in…

A: First of all, we put the reporter gene (GFP) in the diseased cell in which BMP5 is not transcribed.…

Q: You are an expert in DNA-repair mechanisms. You receive a sample of a human cell line derived from…

A: In normal conditions, the cells are capable of fixing the damages caused to DNA before problems…

Q: Find non-cancerous, non--nonsense, point mutation genetic disease. Describe the disease's name and…

A: A point mutation is a mutation that only affects a single nucleotide of nucleic acid. It occurs most…

Q: How can Cas9 technology be used in gene therapy. A. Base editing can be used to repair DNA error…

A:

Q: Contrast the various types of DNA repair mechanisms known to counteract the effects of UV radiation.…

A: A variation is an adjustment in a DNA grouping. Changes can result from DNA duplicating botches made…

Q: Distinguish between spontaneous and induced mutations. Give some examples of mutagens that cause…

A: Mutations are the changes in the genetic material of an organism that are inherited from one…

Q: 20. In class, we discussed different types of genetic change that can cause a normal gene (proto…

A: There are two common causes of most cancers involves mutations in genes called proto-oncogenes and…

Q: 1. Transcription: a)State the role of RNA polymerase in gene transcription.b. Explain why the DNA…

A: Transcription is the process of copying information from a strand of DNA to a newly synthesized…

Q: 45) A patient's mother died from an incurable neurological disease. The patient wants to test his…

A: Neurological diseases are a group of disorders that affect the nervous system, which includes the…

Q: The first mutation is thought to occur in utero in most cases of ALL diagnosed before age 5 years…

A: Acute Lymphoblastic Leukemia (ALL) is a type of blood cancer that affects white blood cells. It is…

Q: Adjacent pyrimidine bases in DNA form dimers with high efficiency after exposure to UV light. If…

A: Skin tanning is the process in which the skin color is darkened as a result of exposure to…

Q: Explain how gene conversion can occur via mismatch repair and DNA gap repair synthesis.

A: Step 1 Gene conversion is the process of replacing a homologous sequence with a deoxyribonucleic…

Q: Which of the following statements about inherited DNA repair syndromes are correct (select all that…

A: DNA repair deficiency disorder:  Generally when DNA undergoes any sort of DNA damage these damages…

Q: Which ONE of the following genetic patterns defines a patient with acute myeloid leukaemia with the…

A: Any kind of alteration in the nucleotide sequence of an organism’s genome is referred to as a…

Q: Retinoblastoma is an extremely rare cancer of the retina in the eye. The disease mainly affects…

A: The investigation into retinoblastoma, a uncommon eye cancer fundamentally influencing children,…

Q: 16) Mutations that occur during the process of DNA replication: Answer: A) almost always lead to…

A: Not all mutation results in genetic disorder. Most of the mutation have no impact on health of a…

Q: Describe and give examples of direct reversal of DNA damage.

A: Direct reversal of DNA Damage is also called Direct Repair.  This system act on damaged nucleotides.…

Q: A mutation in the coding region of a gene may alter the of the gene. protein-coding region may alter…

A: Mutations are changes in the DNA sequence of an organisms genome. DNA is the genetic material that…

Q: ist three ways in which an unrepaired double-stranded DNA break can be highly dangerous to the cell…

A: DNA replication is that the method by that deoxyribonucleic acid makes a duplicate of itself…

Q: Which of the following statements are correct about DNA Repair in mammals (select all that apply)?…

A: DNA mutation is a process by which DNA damages are repaired by various enzymes. If these DNA damages…

Q: Describe four types of point mutations: transitions,transversions, deletions, and insertions.

A: A rapid change in the sequence of DNA (deoxyribonucleic acid) due to physical or chemical factors is…

Q: 1.   Transformation refers to .................................. Group of answer choices a.vertical…

A: Gene transfer: a. It is the mechanism by which DNA is transferred from a donor to a recipient cell.…

Q: Match the concept in column A to the concept in column B. Write the letter of the correct answer on…

A: Molecular biology is the study of biological processes at molecular level. It includes various…

Q: A gene contains the sequence CGCATACGGTAC that results in the amino acid sequence arg-ile-arg- tyr.…

A: The translation is a process where a mature mRNA sequence is converted into respective amino acids…

Q: What are some of the reasons you might expect of human cells to have more efficient repair systems…

A: DNA (deoxyribonucleic acid) repair refers to the set of processes that are involved in the…

Q: What is/are the attributes that make nucleotide excision repair (NER) and base excision repair (BER)…

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that passes genetic information from one…

Q: Despite the failure to date of gene therapy, identification of the gene responsible for cystic…

A: Cystic fibrosis (CF) is a genetic disease caused by a mutation in the CFTR (cystic fibrosis…

Q: Hereditary nonpolyposis colon cancer (HNPCC) is caused by mutations in proteins from one of the DNA…

A: HNPCC is an autosomal dominant inheritance that causes colon cancer in humans. this mutation is…

Q: It has been suggested that it would make the study of human diseases easier if cloned transgenic…

A: Transgenic animals These animals have one or more sequences of DNA from another species have been…

Tissue regeneration & repair

Tissue regeneration involves the restoration of tissue components by regrowth of damaged tissues. In contrast, tissue repair involves patching of injured tissue rather than restoring it. It is the proliferative capacity of the cells that decides the amount of regeneration against the repair that would occur in the tissue. Both regeneration and repair depending on the duration of the injury and response to the inflammation.