Duchenne Muscular Dystrophy (DMD) is a sex- linked, recessive disease in which a mutation in the gene for dystrophin results in muscle cell degeneration. A normal man marries a woman who is a carrier for DMD. a) What are the parent genotypes? b) What are the four possible offspring genotypes from this cross? HINT - do a Punnett Square to figure this out! c) If they have four sons, how many of them will have DMD? C d) If they have eight children, how many will be carriers of DMD? BONUS (+1): Why are males more often affected by sex-linked disorders than females?
Duchenne Muscular Dystrophy (DMD) is a sex- linked, recessive disease in which a mutation in the gene for dystrophin results in muscle cell degeneration. A normal man marries a woman who is a carrier for DMD. a) What are the parent genotypes? b) What are the four possible offspring genotypes from this cross? HINT - do a Punnett Square to figure this out! c) If they have four sons, how many of them will have DMD? C d) If they have eight children, how many will be carriers of DMD? BONUS (+1): Why are males more often affected by sex-linked disorders than females?
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 2QP: Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the...
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