Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Topic Video
Question
In 1995, doctors reported a Chinese family in which
retinitis pigmentosa (progressive degeneration of the
retina leading to blindness) affected only males. All
six sons of affected males were affected, but all of the
five daughters of affected males (and all of the
children of these daughters) were unaffected.
a. What is the likelihood that this form of retinitis
pigmentosa is due to an autosomal mutation
showing complete dominance?
b. What other possibilities could explain the inheritance of retinitis pigmentosa in this family? Which
of these possibilities do you think is most likely?
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution
Trending nowThis is a popular solution!
Step by stepSolved in 3 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A cross is made in tomatoes between a female plant thatis trisomic for chromosome 6 and a normal diploid maleplant that is homozygous for the recessive allele for potato leaf (p/p). A trisomic F1 plant is backcrossed to thepotato-leaved male.a. What is the ratio of normal-leaved plants to potatoleaved plants when you assume that p is located onchromosome 6?b. What is the ratio of normal-leaved to potato-leavedplants when you assume that p is not located onchromosome 6?arrow_forwardplease make sure to read the question (THERE ARE OTHER VARIATIONS OF THE QUESTION ON DIFFERNT WEBSITES THAT ARE DIFFERENT THAN MINE)arrow_forwardTay–Sachs disease is caused by loss-of-function mutations ina gene on chromosome 15 that encodes a lysosomal enzyme.Tay–Sachs is inherited as an autosomal recessive condition.Among Ashkenazi Jews of Central European ancestry, about1 in 3600 children is born with the disease. What fraction ofthe individuals in this population are carriers?arrow_forward
- Goatee A Bearding in goats is inherited as an autosomal trait determined by two alleles, B1 and B2. Interestingly, the bearded trait is recessive in females, while it is dominant in males. In both sexes, homozygotes for the B1 allele are beardless. Which of the following is true? (more than one correct answer possible) Males with the genotype B1B1 are beardless Females with the genotype B1B2 are beardrd Males with the genotype B1B2 are bearded Females with the genotype B1B1 are bearded Females with the genotype B2B2 are beardless. Males with the genotype B2B2 are beardedarrow_forward3) In the snail Capaea nemoralis, an autosomal allele causing a banded shell (B®) is recessive to the allele for an unbanded shell (B°). Genes at a different locus determine the background color of the shell; here yellow (C') is recessive to brown (CBw). A banded, yellow snail is crossed with a homozygous brown, unbanded snail. The F1 are then crossed with banded, yellow snails (a test cross). a. What will the results of the testcross be in the loci that control banding and color ARE linked with NO crossing over.arrow_forwardQuestion 15: Consider the consequence if one of the mutations you tested for complementation was a dominant mutation. You should see that complementation tests could not be used to provide information about dominant mutations. a) If a mutation were dominant how would your interpretation of the phenotype of the diploid be altered? No change would occur v b) How would you test whether any of these trp mutations were dominant? There is no way to test fc Varrow_forward
- Could someone please help me with this grade 11 bio dihybrid cross problem on how to solve this question, using a strategy in detail! Assume that curly hair (C) is dominant to straight hair. Albinism (P ) is recessive to normal skin pigmentation. A woman who is heterozygous for curly hair and albinism has a child. The father is homozygous dominant for curly hair and has albinism. (a) Determine the possible phenotypes for their child. (double-crossing, Punnet square) (how to display the traits) (b) Calculate the four different probabilities of a child beingboth a male and of each phenotype. (steps in solving this) (c) What is the probability that the child will expressalbinism and have curly hair like his father? (steps in solving this)arrow_forwardDue to dosage compensation by X inactivation, females can exhibit a mosaic pattern of sweat glands on only some portions of their body if they carry a particular loss of function allele. Could any of the following genotypes result in males with such a mosaic pattern of sweat glands? Explain. A. X^AY B. X^AX^AY C. X^AX^aY D. Not possiblearrow_forwardSuppose you are testing the null hypothesis that the mode of inheritance for a particular disease in elegant cranes is sex-linked recessive. You employ the following crosses, where R is the wild-type allele, r is the disease allele, and Y is Y-chromosome allele (only in males): Parental cross (Affected male with unaffected (carrier) female): rY x Rr. F₁ cross (Unaffected male with affected female): RY x rr. Suppose you perform these crosses at two different research locations. You obtain the following counts in the F2 generation: Location 01 Male, Disease: 200 Male, Wild-type: 225 Female, Disease: 211 Female, Wild-type: 205, Location 02 Male, Disease: 320 Male, Wild-type: 325 Female, Disease: 354 Female, Wild-type: 310 Do you reject or not reject the null hypothesis that the mode of inheritance is sex-linked recessive at each location? The significance level is 0.01. (Hint: when applying the ChiSq goodness of fit test, if the expected value for a row is 0, remove that row and reduce…arrow_forward
- The inheritance pattern of a rare form of Xeroderma pigmentosum is exhibited in the pedigree shown below. The pattern of inheritance of the Xeroderma pigmentosum phenotype suggests what type of inheritance. please explain your reasoning.arrow_forwardDuchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to walking and breathing difficulties and heart disease. Which of the following is a valid conclusion about the Duchenne muscular dystrophy pedigree shown above? a. Without further evidence, the genotypes of individuals II-2 and III-2 cannot be determined. b. Only individuals I-1 and II-3 are confirmed carriers of the Duchenne muscular dystrophy allele.arrow_forward
arrow_back_ios
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education