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Describe some ways that drugs might act as enzyme inhibitors.
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- Describe the differences between how competitive and non-competitive inhibitors work.Can you explain how ACE inhibitors work?E. Indicate whether each of the following statements describes a: reversible competitive inhibitor reversible noncompetitive inhibitor irreversible inhibitor An inhibitor that decreases enzyme activity by binding to a site on the enzyme other than the active site. An inhibitor that has a shape and charge distribution similar to that of the enzyme's normal substrate. The inhibitor and substrate can bind to the enzyme simultaneously An inhibitor that inactivates enzymes by forming a strong covalent bond at the enzyme active site. Both inhibitor and substrate bind at the active site on a random basis. The inhibitor effect cannot be reversed by the addition of more substrate. Inhibitor structure does not have to resemble substrate structure.