Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?

For cancer to occur in an individual which of the following must occur?   a an accumulation of multiple mutations in many different cells b a deletion of part of a gene c an accumulation of multiple mutations in an individual cell d chromosomal segment deletions e triploidy

Radiotherapy (treatment with ionizing radiation) is one of the most effective current cancer treatments. It works by damaging DNA and other cellular components. In which ways could radiotherapy control or cure cancer, and why does radiotherapy often have significant side effects?

The vast majority of human cancers mutations in the p53 gene. What is the function of p53 normally in the cell? What happens when p53 is mutated? Is this a gain of function or loss of function mutation?

Every year, about a million Americans are diagnosed with cancer. This means that about 75 million Americans now living will eventually have cancer, And one in five will die of the disease. There are many kinds of cancers and many causes, such as smoking, overexposure to ultraviolet rays, a high fat and low fiber diet, and some workplace chemicals. Hundreds of millions of dollars are spent each year on searching for treatment, yet less money is spent on prevention. Should we devote more resources to treating cancer or to preventing it? Explain.

What is the role of regulatory gene mutations in cancer?

p53 iš an important tumor suppressor gene that is activated in response to a variety of stress signals. Upon activation it induces a cell cycle arrest or cell death. Hence, loss-of-function mutations in the p53 gene are found in almost every type of cancer. How do you predict loss-of-function mutations in the DNA binding domain of the p53 protein affect its function? OIt no longer will act as activator of gene expression O It no longer will act as repressor of gene expression O It no longer will act as activator or repressor of gene expression O It no longer will act as coactivator or corepressor

Some cancers have been treated with drugs that demethylate DNA.Explain how these drugs might work. Do you think the cancer-causinggenes that responded to the demethylation are likely to have beenoncogenes or tumor-suppressor genes? Explain your reasoning.

how can mutations in several genes drive cancer?

The belief that cancer results from a single cell that acquired multiple mutations is called:   Question 20 options:   Tissue organization field theory   Genomic instability   Familiar cancers   Driver mutations   Somatic mutation theory of cancer