Can we cure cancer by restoring the function of tumor suppressor proteins such as mutant p53 or pRb? If so, how is this possible?
Q: Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb? If so, how…
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Q: Can restoring tumor suppressor function, such as mutant p53 or pRb, be used to cure cancer? If…
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Can we cure cancer by restoring the function of tumor suppressor proteins such as mutant p53 or pRb? If so, how is this possible?
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- Another model, the random model, proposes that any cell in a malignant tumor has the potential to form a new tumor. Does the cancer stem cell hypothesis contradict this idea?What is the difference between a proto-oncogene and a tumor-suppressor gene?Can restoring tumor suppressor function, such as mutant p53 or pRb, be used to cure cancer? If that's the case, how is it possible?
- Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb? If so, how can this be?What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to cancer?What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53 functions?
- Why is it important to model cancer through the generation of induced pluripotent stem cells ? Please list item by item. Explain in detail the main findings.How can a mutation in a tumor-suppressor gene contribute to the development of cancer?How can a defect in p53 gene contribute to cancer development?
- Why is p53 considered a tumor suppressor protein? Question 12 options: a) Because p53 normally detects breaks in DNA. b) Because p53 normally causes progression from G1 to S phase to halt until damaged DNA is fully repaired. c) Because p53 normally repairs breaks in DNA. d) Because p53 normally stimulates transcription of Repair Polymerase. e) Because p53 normally reduces the mutation rate of DNA polymerase.Is PI3K a proto-oncogene or a tumor suppressor gene? Why?What separates cancer cells from normal cells? Describe one form of mutation that can increase the risk of a normal cell being cancerous.