Base in second position A UUU UCU UAU UGU Phe Tyr UCC Cys C UUC UAC UGC Ser UUA UCA UAA Stop UGA Stop A >Leu UUG UCG UAG Stop UGG Trp G CUU CCU CAU CGU His CUC CCC CAC CGC >Leu Pro Arg CỦA CCA СА CGA Gin CUG CCG CAG CG AUU ACU AAU AGU Asn Ser AUC >lle A AUA ACC AAC AGC Thr ACA AGA Lys AGG AAA Arg AUG Met/ ACG AAG start GUU GCU GAU GGU U Asp GCC GGC GUC G GUA GAC Val Ala Gly A GCA GAA GGA Glu GUG GCG GAG GGG G A FIGURE 5.17 The genetic code. The table is arranged so that users can quickly find any amino acid from the three bases of the mRNA codon (written in the 5' →3' direction). For example, to find the amino acid corre- sponding to the codon 5' AUC 3', look first in the A row, then in the U col umn, and finally in the C space, which indicates that the amino acid is lle. Base in third position (3' end) Base in first position (5' end)

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
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Question

Based on the information in as shown, which single-nucleotide mutation
event is more likely: Arg-to-His, or Arg-to-Ser? Explain.

Base in second position
A
UUU
UCU
UAU
UGU
Phe
Tyr
UCC
Cys
C
UUC
UAC
UGC
Ser
UUA
UCA
UAA
Stop UGA Stop A
>Leu
UUG
UCG
UAG
Stop UGG Trp G
CUU
CCU
CAU
CGU
His
CUC
CCC
CAC
CGC
>Leu
Pro
Arg
CỦA
CCA
СА
CGA
Gin
CUG
CCG
CAG
CG
AUU
ACU
AAU
AGU
Asn
Ser
AUC >lle
A
AUA
ACC
AAC
AGC
Thr
ACA
AGA
Lys
AGG
AAA
Arg
AUG Met/
ACG
AAG
start
GUU
GCU
GAU
GGU
U
Asp
GCC
GGC
GUC
G
GUA
GAC
Val
Ala
Gly
A
GCA
GAA
GGA
Glu
GUG
GCG
GAG
GGG
G
A FIGURE 5.17 The genetic code. The table is arranged so that users
can quickly find any amino acid from the three bases of the mRNA codon
(written in the 5' →3' direction). For example, to find the amino acid corre-
sponding to the codon 5' AUC 3', look first in the A row, then in the U col
umn, and finally in the C space, which indicates that the amino acid is lle.
Base in third position (3' end)
Base in first position (5' end)
Transcribed Image Text:Base in second position A UUU UCU UAU UGU Phe Tyr UCC Cys C UUC UAC UGC Ser UUA UCA UAA Stop UGA Stop A >Leu UUG UCG UAG Stop UGG Trp G CUU CCU CAU CGU His CUC CCC CAC CGC >Leu Pro Arg CỦA CCA СА CGA Gin CUG CCG CAG CG AUU ACU AAU AGU Asn Ser AUC >lle A AUA ACC AAC AGC Thr ACA AGA Lys AGG AAA Arg AUG Met/ ACG AAG start GUU GCU GAU GGU U Asp GCC GGC GUC G GUA GAC Val Ala Gly A GCA GAA GGA Glu GUG GCG GAG GGG G A FIGURE 5.17 The genetic code. The table is arranged so that users can quickly find any amino acid from the three bases of the mRNA codon (written in the 5' →3' direction). For example, to find the amino acid corre- sponding to the codon 5' AUC 3', look first in the A row, then in the U col umn, and finally in the C space, which indicates that the amino acid is lle. Base in third position (3' end) Base in first position (5' end)
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