A congenital defect mutates the genes that code for RAG1 & RAG2 making them unreadable (therefore no RAG1 or RAG2 production). Will this person still be able to produce B cells? Why or Why not

Q: The current estimate is that mammalian B cells are capable of producing 1,010 different…

A: Immunoglobulins are composed of four polypeptide chains out of which two are heavy chains and two…

Q: According to the clonal selection theory, all immunoglobulin molecules in an individual B cell have…

A: *clonal selection theory states that antigen selects lymphocytes for activation from some cells  to…

Q: I figured out that TJ and his brother have chronic granulomatous disease with defective NADPH…

A: Introduction :- Chronic granulomatous disease (CGD) is a rare genetic disorder that affects the…

Q: 28. The molecules mediating signal transduction on a B-cell following antigen binding to BCR are…

A: B cell It is a type of lymphocyte which is involved in providing the humoral immunity component of…

Q: Explain the typical immunophenotypic features of peripheral B cells in: (i) X-linked…

A:

Q: about B cells in the following is: They can present both protein and non-protein antigens They can…

A: The immune system is a control network of organs and immune cells that detect and kill foreign…

Q: This was the HIPPo pathway diagram given to us by our physiology Lecturer. Can you please kindly…

A: The Hippo pathway is a highly conserved signaling pathway that plays a crucial role in controlling…

Q: B lymphocytes, the precursors of plasma cells, are triggered to proliferate by the binding of…

A: B-cell is a type of lymphocyte which is involved in the humoral immune response in the body. B-cell…

Q: Emil has fallen and scratched a wound on his knee. After a while, the knee swells and aches at the…

A: The entire activity of the immune system in tackling infection is depicted in the figure given.

Q: How and why do B cells undergo a class switch from producing IgM antibodies to any of the other Ig…

A: Class exchanging happens after initiation of a develop B cell through its layer bound neutralizer…

Q: Please answer fast Which type of cells normally drive class switching to IgE and how? How might the…

A: Answer

Q: Why is infectious mononucleosis also called the “kissing disease”?

A: Virus is a microorganism that is neither prokaryotic or eukaryotic. This is because the virus…

Q: Describé combination in develőpment ôf cell. Inclüde in your description the roles of RSS, RAG-1 and…

A: Answer :: Recombination activating gene (RAG) products are required for the rearrangement of antigen…

Q: For question with blanks, choose the combination of answers that most accurately completes the…

A: Immunology is a part of science that covers the investigation of immune frameworks taking all things…

Q: Name the cells which are : (i) double negative T cells (ii) double positive T cells

A: T cells are a part of immune system and develop from stem cells in the bone marrow. They protect the…

Q: Using the letters from column B, match the cell description in column A. (Note that all require more…

A: Different immune cells are involved in mediating protection to the host against the pathogen. There…

Q: The following events elicit an antibody response to a T-dependent antigen (Ag). Put them in order…

A: "Since you have posted multiple questions, we will provide the solution only to the first question…

Q: Which of the following are strategies do cancer cells use to escape detection by the immune system?…

A: We realize that the Immune system can perceive and can kill cancer cells. Either cancer cells or…

Q: Tuberculosis is a chronic respiratory condition caused by Mycobacterium tuberculosis, a high…

A: Tuberculosis is caused by Mycobacterium tuberculosis.

Q: Would a denatured antigen be expected to have the same epitopes as its native (undenatured)…

A: An epitope is a small part in antigen. This portion of antigen is recognized by antibody. They may…

Q: The head of the oncology divison of a large biotech company proposes to develop a therapeutic…

A: For cancer treatment, there are several options. The treatment a patient receives depends on the…

Q: List key mechanisms that allow an individual to potentially generate a repertoire (collection) of B…

A: The immune system of our body may produce a large number of B cells that can recognize a wide…

Q: Write T if the statement is correct; write F if the statement is not correct. P and E selectins are…

A:

Q: Why is the response to T-independent antigens important medically?

A: Importance of T independent antigen medically -- T cells  -- These are type of lymphocyte ,White…

Q: DiGeorge syndrome is a congenital disease that results in a poorly developed, nonfunctioning thymus…

A: Primary immunodeficiency are the immunodeficiency diseases which arises from the birth where as…

Q: What happens when a helper T cell is activated?

A: An example of an immune cell is the helper T-cell. They are among the major cell types that are…

Q: How can a B cell have both IgM and IgD on its surface?

A: * B cells produce from lymphoid progenitor cell which develop in fetal liver and later in bone…

Q: VDJ rearrangement occurs so that: Select one: a.after a pathogen has entered the system, B cells…

A: VDJ arrangement or VDJ recombination is the specialized mechanism which takes place in developing…

Q: Explain your understanding of the immune system and phagocytosis (including the different stages).

A: In this condition olajumoke is suffering with painful condition where she is facing pain and grief…

Q: T cells have to work in a partnership with an Antigen Presenting Cell (APC). Before this can occur,…

A: Antigen Presenting Cells (APC) are phagocytic cells which engulfs pathogens. Some example of APC are…

Q: Explain how dendritic cells or B cells can express six different versions of MHC1 and six to eight…

A: An antigen is a substance or a molecule that the body recognizes as a foreign particle. That means…

Q: Which of the following statements is TRUE about NK cells? Select an answer and submit. For keyboard…

A: Natural Killer (NK) cells are a type of cytotoxic immune cell that play a role in the rejection of…

Q: Reed Sternberg cells are derived from which type of normal cell?   T-cells   B-lymphocytes…

A: Immune system is system which helps our body to fight against the foreign substances which will…

Q: Cancer cells often underexpress MHC class 1 molecules. Due to these characteristics, they may be the…

A: MHC class I molecules are heterodimers containing a heavy chain of about 350 amino acids and a light…

Q: Progression from early-stage HIV disease to AIDS can beexpected within a few months:(a) In nearly…

A: HIV is also known as the human immunodeficiency virus is the virus that causes AIDS (acquired…

Q: Why are helper T cells sometimes called CD4 or T4 cells?Why are cytotoxic T cells sometimes called…

A: T cells are classified into three types :  T- helper cells cytotoxic T cells regulatory T cells T…

Q: Match the stage of B cell development with the rearrangement or expression of immunoglobulin genes.…

A: B cell development begins in the fetal liver and continues in the bone marrow throughout our lives.…

Q: How would this illustration change if it showed class switching by B cells residing in Peyer’s…

A: Class Switching is a type of biological mechanism that converts the production of a B-cell's…

Q: e class of immunoglobulins which can cross the placenta is -

A: Immunoglobulins, additionally referred to as antibodies, are compound protein molecules made by…

Q: In B cells, what mechanism ensures that only rearranged V genes are transcribed?

A: A gene (from genos (Greek) which means generation or birth or sex) is a basic unit of heredity and a…

Q: a) How does Venetoclax, a BH3 mimetic, function in increasing cellular death? In your answer make…

A: Venetoclax attaches to a protein called Bcl-2. This protein is present in high amounts in CLL cancer…

Q: What problems would arise if a person had a hereditary deficiency that resulted in an inability to…

A: Malnutrition is the key component which cause immunodeficiency. It occur when one or more…

Q: Both NK cells and cytotoxic T cells "kill" via the same mechanisms - what are they?  Are these cells…

A: Immunity is the capability of multicellular organisms to resist harmful microorganisms. Immunity…

Q: What two functions do the follicular dendritic cells provide B cells?

A: Follicular dendritic cells or FDC s are one type of specialized antigen presenting dendritic cell…

Q: Macrophages typically present antigens to T cells. However, macrophages that reside in the…

A: Macrophages are a type of white blood cell that engulf and digest cellular debris, foreign…

Q: Some immune system cells like B lymphocytes and T lymphocytes must first be "trained" in either the…

A: The complex network of organ, cells and proteins in our body that defends our body against infection…