A congenital defect mutates the genes that code for RAG1 & RAG2 making them unreadable (therefore no RAG1 or RAG2 production). Will this person still be able to produce B cells? Why or Why not

picture 1 shows the directed migration of two immune cell types, neutrophils (red) and macrophages (green) to a laser-induced injury in the ear of a mouse. As you can observe from the video, there are three stages to this process: 1) an initial phase characterized by fast recruitment of neutrophils (red) to the site of injury followed by 2) the slower recruitment of macrophages after which 3) the interaction between both cell types is stabilized. Recruitment to the injury site is mediated by leukotriene B4 (LTB4), a potent immune signaling molecule (Figure 1A). LTB4 binds to BLT1, a G-protein coupled receptor (GPCR), activating various signaling pathways and resulting in immune cell migration to the site of injury (Figure 1B). With this background information and your knowledge of cell and molecular biology, describe in detail in your own words, as many molecular processes as you can identify that must take place for the cell migration process depicted in the video to be achieved. For…

What are two types of long-lived cells derived from the B cell lineage? Where are these cells located + what is their function?

Interferons can slow down viral replication by inhibiting protein synthesis in in body cells. a.) true  b.) false

B cell receptor diversity is behind our ability to fight new infections. However, epitope-specific B Cell memory is critical for the secondary immune response protecting against new infections. You are ready to integrate concepts. In this question, you will combine B Cell receptor diversity and cloning! Please answer each question in less than 150 characters (including spaces). 1.Can a mature B Cell produce an epitope-specific antibody first and then switch to make an antibody against a different epitope? Explain.   2.Please describe what is transferred into an egg during cloning by somatic nuclear cell transfer.   3.How many B Cell receptors/antibodies could be generated in a mouse cloned by somatic nuclear cell transfer from a mature B Cell (after recombination)?

Why are Helper T cells only responsive to antigen presenting cells (APC)?

This cell type is thought to initiate the demyelination associated with MS       T cell     Microglial cell     Astrocyte         Natural killer (NK) cell       Oligodendrocyte     Macrophage       B cell

A 55-year-old male was diagnosed with rheumatoid arthritis (RA) after experiencing complications from an infection during his youth. Rheumatoid arthritis is an autoimmune disease that manifests as chronic inflammation, primarily in the joints. The patient states that he manages his symptoms well and lives a lifestyle that attempts to keep the inflammation at a minimum. (CD4 T helper cells and other immune cells in a patient with RA promote cytokine release, especially release of interleukin-1 (IL-1) and tumor necrosis factor (TNF)). Having lived with RA for most of his life, this patient is well aware of the inflammatory response and how it feels when he is experiencing exacerbations. During times of increased inflammation, which of the following laboratory results is most likely to be abnormal? Choose the correct answer and give a brief explanation. A). White blood cell count B). Glucose C). Red blood cell count D). Erythrocyte sedimentation rate (ESR)

Where do B-cells proliferate and mature? Group of answer choices Thymus Red bone marrow Liver Small intestine

What is the function of interleukin-7 in lymphocyte formation? View Available Hint(s) Hint 1. Development of Lymphocyte Types  opened hint The different lymphocyte types are all derived from lymphatic stem cells.  Their ultimate fate depends upon the location where they mature and the signals that they receive.    What is the function of interleukin-7 in lymphocyte formation? It supports the differentiation of lymphoid stem cells into NK, B, and T cells. It supports the differentiation of pluripotential stem cells into lymphoid stem cells. It supports the differentiation of pluripotential stem cells into NK, B, and T cells. It supports the differentiation of lymphoid stem cells into NK cells and B cells.