15. G + C Content: Describe how the G+C content of an organism can be measured. In your response, be sure to address the following: c. Does a similarity in G + C content between two organisms mean that they are necessarily related? Explain. What other information might help determine relatedness between two organisms? Besure to define any terms and be complete and specific in your response.

Q. In hemoglobin protein, an ion pair exists between lysine at position 40 (pka 10) and a beta-chain terminal carboxyl (pka 4). What fraction of these Lys-40/beta-carboxyl are actually in an ion pair at ph 7? а. О b. 0.1 C. 0.5 d. 0.9 е. 1.0

distribution of Benzene in a 4-compartment PBK model after an exposure of 6h. Convert Berkeley Madonna code to Matlab.  Note: The parameters in the table below are for a mouse model. 1a) What are the two type of products containing Benzene consumers were recently concerned about. Which of these two different type of products is likely more harmful? (hint: check news/reports and social media channels)   1b) Plot Jresp along with the concentrations of Benzene in blood, fat, non-fat and liver in a 24h window (pdf). Why is Jresp slightly decreasing within 6h of exposure? Here is the Berkeley Madonna code: {Top model}   METHOD RK4   STARTTIME = 0 STOPTIME = 24 DT = 0.02        {Reservoirs Blood, Fat, NonFat and Liver}    d/dt (NF) = + Jnf       INIT NF = 0    d/dt (F) = + Jf       INIT F = 0    d/dt (B) = - Jnf - Jf - Jl + Jresp       INIT B = 0    d/dt (L) = + Jl - Jmetab       INIT L = 0      {Flows}    Jnf = Qnf*(Cb-Cnf)    Jf = Qf*(Cb-Cfv)    Jl = Ql*(Cb - Clv)    Jmetab = vmax*Cl/(Km +…

ati. Question: 26 of 45 On February 2 of each year, the United States observes the unusual holiday of Groundhog Day, a day of hope that winter is over and spring is beginning. This tradition has been officially observed in the U.S. since the 1800s, and is believed to have developed from European folk traditions in which a bear, fox, badger, or even hedgehog would serve as the symbolic meteorologist. Although other cultures and towns observe Groundhog Day (or something similar), the town of Punxsutawney, Pennsylvania takes special pride in being home to the one true forecasting groundhog, Punxsutawney Phil. At the turn of the twentieth century, townspeople formed the Punxsutawney Groundhog Club to perpetuate the joyful rituals and events surrounding Groundhog Day. Over the years, these events have come to include a scavenger hunt, a talent show, and a ball. A Legend has it that on Groundhog Day the official weather forecasting groundhog awakens from hibernation and comes out of his…

Please note whether each protein is either a Kinase (K), ATPase (A), GTPase (G), Membrane protein (M). Some proteins may need more than one letter: Dynamin [Choose ] Porin [Choose ] EGF Receptor [Choose ] CD4 [Choose ] P-glycoprotein [Choose ] Rho [Choose ] <

When conducting research involving human participants and it will include a survey on fear of COVID-19.Is it need to apply for approval of IRB before the conduct of the study? why?

Why does the dissociation constant change for hemoglobin in high and low 02 concentrations? O Hemoglobin is a tetramer and subunits have decreased dissociation of 02 when a neighboring subunit has bound 02 O Hemoglobin is a monomeric protein with increased dissociation of 02 when a neighboring molecule has bound 02 O Hemoglobin is a tetramer and subunits have increased dissociation of 02 when a neighboring subunit has bound CO O Hemoglobin is a tetramer and subunits have increased dissociation of O2 when a neighboring subunit has bound O2

. The mutation in hemoglobin at B82 Lys → Asp results in lowered O2-binding affinity compared to normal hemoglobin. B82 is one of the residues that lines the 2,3-BPG binding site. A rationale for the observed reduction in O2-binding affinity is: A. The positive charge on the Asp side chain can form salt bridges with other negative charged side chains stabilizing R-conformer. B. The negative charge on the Asp side chain can form salt bridges with other positive charged side chains stabilizing the T-conformer. C. The Asp side chain mimics the positive charge on BPG. D. The Asp side chain mimics the negative charge on BPG. E. The Asp side chain is a nucleophile that attacks the BPG. F. BPG attacks the Asp side chain. G. Stabilization of the R-conformer favors O, release. H. Stabilization of the T-conformer favors O, release.

Given the parameters below:1. u(max) = 1.0/ h Ks = 10 uM2. u(max) = 0.7/h Ks = 2 uM) a. sketch the comparative Substrate Concentration vs.u(max) graphs for 1.  b. sketch the comparative Substrate Concentration vs.u(max) graphs for 2.  (answer a and b)

5. Anesthetic gases used in surgery are known to bind to the hemoglobin molecule in red blood cells. The diagram below illustrates O2 binding curves of normal human HbA in the presence of the anesthetic gas dichloromethane (DCM). O UNTREATED 100 Symbols: a Dсм 23 Torr • DCM 50 Torr x DCM I00 Torr o, 0 Torr DCM; О, 23 Torr DСМ Д, 50 Torr DСМ x, 100 Torr DCM. 80 60 40 (1 Torr = 1 mm Hg.) 20 The solutions were buffered to pH 7.4. 0.5 1.0 1.5 2.0 log p02 For the curves at 0 and 100 Torr of dichloromethane, draw their equivalent in the form of (a) (* Hill plots. Label the axes and indicate on both the plot above and the Hill plot where the value of the dissociation equilibrium constant Kd for O2 binding is defined for 0 and 100 Torr of dichloromethane Kd Hb(O2)n nO2 Hb + Be sure to label the axes, indicate the units on both axes, and make the Hill plot so that the values of Kd are equivalent to those on the saturation plot above. Indicate whether cooperativity, as indicated by the Hill…