Chapter 29.SE, Problem 17VC

Interpretation Introduction

a)

Interpretation:

To identify the amino acid that is a catabolic precursor of the given α-keto acids:

Answer to Problem 17VC

Explanation of Solution

Catabolism of proteins occurs by a discrimination of α – amino acids according to the following reaction:

Conclusion

The retro symmetric strategy is used to derive synthons and starting materials.

Interpretation Introduction

b)

Interpretation:

To identify the amino acid that is a catabolic precursor of the given α-keto acids:

Answer to Problem 17VC

The corresponding α amino acid precursor is respectively:

Explanation of Solution

Catabolism of proteins occurs by a discrimination of α – amino acids according to the following reaction:

Thus, the α – keto acid derives its structure from its precursor parent amino acid by replacing the segment by .

This proves the above assigned structures for the α – amino acids.

Conclusion

The retro symmetric strategy is used to derive synthons and starting materials.