Human Physiology: An Integrated Approach (8th Edition)
Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 9.3, Problem 9CC
Summary Introduction

To determine: The two metabolic pathways for aerobic metabolism of glucose.

Introduction: The process of producing energy in the presence of oxygen is known as aerobic respiration. This process occurs only in the cytoplasm and mitochondria. Oxygen is the basic requirement for aerobic respiration. The aerobic respiration takes place only in the presence of molecular oxygen.

Summary Introduction

To determine: The use of NADH produced in two metabolic pathways that are involved in the aerobic metabolism of glucose.

Introduction: Glucose is a six-carbon molecule that metabolizes aerobically to produce energy. The two pathways that are used for aerobic metabolism of glucose are glycolysis and citric acid cycle.

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If α-ketoglutarate is removed from TCA cycle and used to make glutamate, how many of each of the cofactors (not intermediates) and high energy molecules in the TCA cycle are lost? How much ATP does this equate to (NADH = 2.5 ATP, FADH2 = 1.5 ATP)?
Which of the following statements about the pentose phosphate pathway (PPP) is true? (A) The purpose of the pentose phosphate pathway is to produce NADH for use in anabolic pathways and ribose 6-phosphate for nucleotide synthesis.(B) The oxidative arm of the PPP produces (2) NADPH per glucose 6-phosphate that enters the pathway. (C) Phosphopentose isomerase converts the ribose 5-phosphate made in the oxidative arm of the PPP into ribulose 5-phosphate that is used to form the ribose sugar of nucleotides.(D) The non-oxidative arm of the PPP interconverts between ribose 5-phosphate and a variety of intermediates of b-oxidation. (E) One of the functions of the PPP is to provide NADPH that inhibits glutathione reductase so that it cannot oxidatively damage RBCs.
The conversion of glyceraldehyde-3-phosphate into 1,3-bisphosphoglycerate reduces NAD+ to NADH. Under anaerobic conditions, how is NADH oxidized back to allow for continuing glycolysis? (name the compounds involved in the reaction besides NADH and their draw structures)

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Human Physiology: An Integrated Approach (8th Edition)

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Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY