(a)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the
Addition of water to the given starting material creates bifunctional compound.
(b)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(c)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(d)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
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Chapter 9 Solutions
Organic Chemistry (8th Edition)
- Please devise syntheses of the product compounds below from their respective starting materials. Each of the synthesis will require multiple steps.arrow_forwardShow the step by step synthesis of the following compound.arrow_forwardProvide a synthesis for the following reaction. If more than one step is required be sure to number separate steps.arrow_forward
- Draw a possible forward synthesis to form the following compounds using MeOH, ETOH, NaCN and benzene as the only carbon sources. You can use any other reagents so long as they are not a source of carbon in the target molecule. A synthesis may use any previous compound as a reagent. Use retrosynthetic analysis to help. There may be more than one correct answer to each problem. НО Но OH j) k) h) HNarrow_forwardch1arrow_forwardWhat would be the optimal conditions to achieve the following synthesis? дон dilute H₂SO4 concentrated H₂SO4 dilute HBr concentrated HBr aqueous NaOHarrow_forward
- 2) Outline a synthesis for each the target molecule shown below given the starting material. Br ZI N Harrow_forwardProvide a plausible synthetic pathway for the following organic transformation starting with acetic acid. Include a step-wise synthesis and show all the reagents used (on top and below the arrows). но ČH 3arrow_forwardWrite out the complete forward synthesis of the target molecule below beginning with the precursor shown. Be sure to include all reagents necessary for each reaction step (may require more than one step)arrow_forward
- a) Propose a synthesis route to prepare the following product from the given starting material. Note that more than one step reaction is required and you must show all the reaction steps including preparation of the intermediates.arrow_forwardPropose a synthesis for the molecular target below. For your synthesis you can use: the given alkyne, any hydrocarbon (compounds that contain only C and H), and any inorganic acid or base. Any other reactants must be synthesized from allowed starting materials, e.g., if your synthesis requires an alkyl halide, you will have to show how the alkyl halide is synthesized from a hydrocarbon. Targetarrow_forwardGiven a target molecule below, propose a synthetic route involving either the Wittig reaction or HornerEdmonson approach. Justify your choice, considering both reagents and selectivityarrow_forward
Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning