Campbell Essential Biology (7th Edition)
7th Edition
ISBN: 9780134765037
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 8, Problem 11SQ
Although nondisjunction is a random event, there are many more people with an extra chromosome 21, which causes Down syndrome, than people with an extra chromosome 3 or chromosome 16. Explain.
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In general, why do changes in chromosome structure or numbertend to affect an individual’s phenotype? Explain why somechanges in chromosome structure, such as reciprocal translocations,do not.
A man who is a carrier of a translocated 15/21 chromosome marries a genotypically normal woman.
(1). Show the possible gametes that will be formed by this man if the translocated 15/21 chromosome synapses with chromosome 21 at Prophase I.
(2). What is the probability that the first child of the couple will be a phenotypically normal girl?
(3). What is the probability that the first child of the couple will be a genetically normal boy?
In a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are trisomic, while 5% have diploid number of chromosomes. Explain this discrepancy.
Chapter 8 Solutions
Campbell Essential Biology (7th Edition)
Ch. 8 - Which of the following is not a function of...Ch. 8 - In what sense are the daughter cells produced by...Ch. 8 - Why is it hard to observe individual chromosomes...Ch. 8 - A biochemist measures the amount of DNA in cells...Ch. 8 - What phases of mitosis are opposite in terms of...Ch. 8 - Complete the following table to compare mitosis...Ch. 8 - If an intestinal cell in a dog contains 78...Ch. 8 - A micrograph of a dividing cell from a mouse shows...Ch. 8 - Prob. 9SQCh. 8 - Prob. 10SQ
Ch. 8 - Although nondisjunction is a random event, there...Ch. 8 - Prob. 12IMTCh. 8 - Prob. 13IMTCh. 8 - For each statement, identify which major theme is...Ch. 8 - A mule is the offspring of a horse and a donkey. A...Ch. 8 - You prepare a slide with a thin slice of an onion...Ch. 8 - Interpreting Data The graph shows the incidence of...Ch. 8 - If an endangered species can reproduce by...Ch. 8 - Every year, about a million Americans are...Ch. 8 - The practice of buying and selling gametes,...Ch. 8 - Prob. 21BS
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- Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies of chromosome 8 are absolutely identical, at what point during meiosis did the nondisjunction event take place?arrow_forwardVariations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.arrow_forwardHuman sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forward
- From 2 to 6 percent of people with autism have an extra chromosome that consists of two long arms of chromosome 15. It includes two copies of the chromosome 15 centromere. Two normal copies of the chromosome are also present. What type of chromosome abnormality in a gamete can lead to this karyotype, which is called isodicentric 15?arrow_forwardA normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable? If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?arrow_forwardTwo phenotypically normal parents produce a phenotypicallyabnormal child in which chromosome 5 is missing part of its longarm but has a piece of chromosome 7 attached to it. The child alsohas one normal copy of chromosome 5 and two normal copies ofchromosome 7. With regard to chromosomes 5 and 7, what do youthink are the chromosomal compositions of the parents?arrow_forward
- A phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?arrow_forwardA phenotypically normal individual has the following combinations of normal and abnormal chromosomes:The normal chromosomes are shown on the left in each pair.Suggest a series of events (breaks, translocations, crossovers, etc.)that may have produced this combination of chromosomes.arrow_forwardTwo phenotypically unaffected parents produce two children withfamilial Down syndrome. With regard to chromosomes 14 and 21,what are the chromosomal compositions of the parents?arrow_forward
- A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?arrow_forwardHow does nondisjunction lead to abnormalities in chromosome number? Describe two types of genetic disorders that can result from nondisjunction.arrow_forwarddescribe a specific example of chromosome abnormality that leads to human cancers, such as leukemia, other than the Philadelphia chromosome that is derived from the translocation of chromosome 9 and 22arrow_forward
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