Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 6, Problem 7PDQ

Why do human monosomies most often fail to survive prenatal development?

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How is it that some chromosomal abnormalities are incompatible with life as early as immediately after fertilization, others may lead to spontaneous abortion within the gestation period, while others may lead to babies born but eventually expire?
Why do most cases of Down syndrome originate from the mother? And how is this linked to maternal age ?
What causes most of the phenotypic abnormalities in someone with Down's Syndrome? A) They have many gene mutations that produce nonfunctional proteins. B) They express too much of some proteins during development. C) Their cells cannot go through mitosis properly during development because they have an odd number of chromosomes. D) Their chromosomes cannot pair during meiosis.

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Essentials of Genetics (9th Edition) - Standalone book

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY