Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 51.5, Problem 4R
Summary Introduction
To review:
The role of active secretion of hydrogen ions (H+) ions by the renal tubule in increasing the bicarbonate concentration in the blood.
Introduction:
Bicarbonate ions (HCO3- ions) in the blood carry carbon dioxide to the lungs for its removal from the body. The concentration of these bicarbonate ions in blood is maintained by the excretion of H+ ions from the tubular cells.
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Describe the components of the glomerular filtration barrier. Explain the importance of the negative electric charge of the different parts of the
glomerular filtration barrier. How does it do to prevent the loss of proteins in the urine?
How do Na-H exchangers on the luminal surface of tubular cells promote bicarbonate reabsorption in the renal tubules?
Renal tubules cannot reabsorb HCO3–; yet HCO3–concentration in the tubular fluid falls while in the blood plasma itrises. Explain this apparent contradiction.
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Life: The Science of Biology
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- Explain how the kidneys help to maintain the balance of acids and bases in extracellular fluid.arrow_forwardA urinalysis reveals that the patients urine contains glucose, hemoglobin, and white blood cells (pus). Are any of these substances abnormal in urine? Explain.arrow_forwardWhich of the following does not contribute to the process of filtration? (a) active transport by epithelial cells lining renal tubules (b) large surface area for filtration (c) low permeability of glomerular capillaries (d) high hydrostatic blood pressure in glomerular capillaries (e) podocytesarrow_forward
- Fatty tissue holds the kidneys in place. Extremely rapid weight loss may cause this tissue to shrink so that the kidneys slip from their normal position. On rare occasions, the slippage can put a kink in one or both ureters and block urine flow. Suggest what might then happen to the kidneys.arrow_forwardReabsorption of HCO3 − is always tied to the secretion of which ion?arrow_forward
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