Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 50.4, Problem 3CC
Summary Introduction
To predict: Whether a mutation in the mice have acted in the signaling pathway that had disrupted its ability to taste bitter, umami and sweet, but not salty and sour.
Concept introduction: Animals utilize their senses (chemical) for various purpose like recognizing the territory (marked), finding mates and navigating at the time of migration and in many other things. In all the animals, for the purpose of feeding behavior, chemical senses are essential. Perceptions of taste (gustation) depends upon the chemoreceptors.
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What is signal transduction? Illustrate and describe the molecular events in signal transduction pathways involving 1) G-protein-coupled receptors and 2) enzyme linked receptors.
Put the steps of the process of signal transduction in the order they occur (hint - try to decide
which signaling pathway this is before working on the order):
1. A conformational change in the signal-receptor complex activates an enzyme.
2. Protein kinases are activated.
3. A signal molecule binds to a receptor.
4. Target proteins are phosphorylated.
5. Second messenger molecules are released.
O 1, 2, 3, 4, 5
O 3, 1, 2, 4, 5
O 1, 2, 5, 3, 4
O 3, 1, 5, 2, 4
I
a) Create a diagram which illustrates the typical signalling mechanism of action of kinase-
linked receptors and possible routes of communication (autocrine etc.). Should show the
specific molecules involved, the mechanisms of signal transduction and indicate the
different pathways that are activated. It should include a specific example of a receptor,
ligand and signalling pathway for each general class. Include as wide a variety of ligands
and modes of action as you can. for a novel pathway.
Superfamily
Give the superfamily to which the receptor belongs
Accession
Give the Uniprot accession number
Name
Give the molecule name
Species
Give the species
Ligand
What is the ligand, or class of ligands which bind to this receptor?
What are the physiological processes involved? Is this autocrine,
paracrine or endocrine or some combination of them? What is the
pathology of the receptor?
Key
physiological
process
involved
Mechanism of What are the downstream actions of the receptor? Which…
Chapter 50 Solutions
Campbell Biology
Ch. 50.1 - Prob. 1CCCh. 50.1 - Prob. 2CCCh. 50.1 - Prob. 3CCCh. 50.2 - How are otoliths adaptive for burrowing mammals,...Ch. 50.2 - Prob. 2CCCh. 50.2 - Prob. 3CCCh. 50.2 - Prob. 4CCCh. 50.3 - Contrast the light-detecting organs of planarians...Ch. 50.3 - Prob. 2CCCh. 50.3 - Prob. 3CC
Ch. 50.3 - Prob. 4CCCh. 50.4 - Explain why some taste receptor cells arid all...Ch. 50.4 - Prob. 2CCCh. 50.4 - Prob. 3CCCh. 50.5 - Contrast the role of Ca2+ in the contraction of a...Ch. 50.5 - Prob. 2CCCh. 50.5 - Prob. 3CCCh. 50.6 - Contrast swimming and flying in terms of the main...Ch. 50.6 - MAKE CONNECTIONS. Peristalsis contributes to the...Ch. 50.6 - WHAT IF? When using your arms to lower yourself...Ch. 50 - Sensory receptors transduce stimulus energy and...Ch. 50 - How are music volume and pitch encoded in signals...Ch. 50 - Prob. 50.3CRCh. 50 - Prob. 50.4CRCh. 50 - What are two major functions of ATP hydrolysis in...Ch. 50 - Which of the following sensory receptors is...Ch. 50 - The middle ear converts (A) air pressure waves to...Ch. 50 - Prob. 2TYUCh. 50 - Prob. 3TYUCh. 50 - Prob. 4TYUCh. 50 - Although some sharks close their eyes just before...Ch. 50 - Prob. 6TYUCh. 50 - EVOLUTION CONNECTION In general, locomotion on...Ch. 50 - Prob. 8TYUCh. 50 - WRITE ABOUT A THEME: ORGANIZATION In a short essay...Ch. 50 - SYNTHESIZE YOUR KNOWLEDGE Bloodhounds, which are...Ch. 50 - If an egg rolls out of the nest, a mother greylag...
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