Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 5, Problem 3NST
In Drosophila, a heterozygous female for the X-linked recessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred in the following
No other phenotypes were observed.
- (a) What is the genotypic arrangement of the alleles of these genes on the X chromosome of the female?
- (b) Determine the correct sequence and construct a map of these genes on the X chromosome.
- (c) What progeny phenotypes are missing? Why?
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In drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm.
(A) Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male.
(B) From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s?
(C) If m-m- females produce useless eggs, then how are m-m- produced?
In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9
No other phenotypes were observed.(a) Determine the correct sequence and construct amap of these genes on the X chromosome ?
: In Drosophila, yellow body is due to an X-linked gene that is recessive to the gene forgray body.(a) A homozygous gray female is crossed with a yellow male. The F1 are intercrossed toproduce F2. Give the genotypes and phenotypes, along with the expected proportions, of theF1 and F2 progeny.(b) A yellow female is crossed with a gray male. The F1 are intercrossed to produce the F2.Give the genotypes and phenotypes, along with the expected proportions, of the F1 and F2progeny.(c) A yellow female is crossed with a gray male. The F1 females are backcrossed with graymales. Give the genotypes and phenotypes, along with the expected proportions, of the F2progeny.(d) If the F2 flies in part b mate randomly, what are the expected phenotypic proportions offlies in the F3??
Chapter 5 Solutions
Concepts of Genetics (12th Edition)
Ch. 5 - In a family with one autistic child the risk for...Ch. 5 - Given that the prenatal test can provide only a...Ch. 5 - Consider two hypothetical recessive autosomal...Ch. 5 - With two pairs of genes involved (P/p and Z/z), a...Ch. 5 - In Drosophila, a heterozygous female for the...Ch. 5 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 5 - Review the Chapter Concepts list on page 94. Most...Ch. 5 - Describe the cytological observation that suggests...Ch. 5 - Why does more crossing over occur between two...Ch. 5 - Explain why a 50 percent recovery of...
Ch. 5 - Why are double-crossover events expected less...Ch. 5 - What is the proposed basis for positive...Ch. 5 - What two essential criteria must be met in order...Ch. 5 - The genes dumpy (dp), clot (cl), and apterous (ap)...Ch. 5 - Colored aleurone in the kernels of com is due to...Ch. 5 - In the cross shown here, involving two linked...Ch. 5 - In a series of two-point mapping crosses involving...Ch. 5 - Two different female Drosophila were isolated,...Ch. 5 - In Drosophila, a cross was made between femalesall...Ch. 5 - Another cross in Drosophila involved the...Ch. 5 - In Drosophila, Dichaete (D) is a mutation on...Ch. 5 - Drosophila females homozygous for the third...Ch. 5 - In Drosophila, two mutations, Stubble (Sb) and...Ch. 5 - If the cross described in Problem 18 were made,...Ch. 5 - Are mitotic recombinations and sister chromatid...Ch. 5 - What possible conclusions can be drawn from the...Ch. 5 - An organism of the genotype AaBbCc was testcrossed...Ch. 5 - Based on our discussion of the potential...Ch. 5 - Traditional gene mapping has been applied...Ch. 5 - DNA markers have greatly enhanced the mapping of...Ch. 5 - In a certain plant, fruit is either red or yellow,...Ch. 5 - Two plants in a cross were each heterozygous for...Ch. 5 - A number of humanmouse somatic cell hybrid clones...Ch. 5 - A female of genotype produces 100 meiotic tetrads....Ch. 5 - In laboratory class, a genetics student was...Ch. 5 - Drosophila melanogaster has one pair of sex...Ch. 5 - In Drosophila, a female fly is heterozygous for...Ch. 5 - The gene controlling the Xg blood group alleles...Ch. 5 - Prob. 34ESP
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- One of the X chromosomes in a particular Drosophila female had a normal order of genes but carried recessive alleles of the genes for yellow body color (y), vermilion eye color (v), and forked bristles (f), as well as the dominant X-linked Bar eye mutation (B). Her other X chromosome carried the wild-type alleles of all four genes, but the region including y+, v+, and f+ (but not B+) was inverted with respect to the normal order of genes. This female was crossed to a wild- type male in the cross diagrammed her. The cross produced the following male offspring:* table in figure a. Why are there no male offspring with the allele combinations y v f+, v+ v+ f, y v+ f+, or y+ v f (regardless of the allele of the Bar eye gene)?b. What kinds of crossovers produced the y v f b+ and v+ y+ f+ B offspring? Can you determine any genetic distances from these classed of progeny?c. What kinds of crossovers produced the y+ v f+ B+ and y v+ f B offspring?arrow_forwardIn Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What progeny phenotypes are missing? Why?arrow_forwardOne of the X chromosomes in a particular Drosophila female had a normal order of genes but carried recessive alleles of the genes for yellow body color (y), vermilion eye color (v), and forked bristles (f), as well as the dominant X-linked Bar eye mutation (B). Her other X chromosome carried the wild-type alleles of all four genes, but the region including y+, v+, and f+ (but not B+) was inverted with respect to the normal order of genes. This female was crossed to a wild-type male in the cross diagrammed her. The cross produced the following male offspring: Y v f B 48 y+ v+ f+ B+ 45 y v f B+ 11 y+ v+ f+ B 8 y v f B 1 y+ v+ f+ B+ 1 a. Why are there no male offspring with the allele combinations y v f+, v+ v+ f, y v+ f+, or y+ v f (regardless of the allele of the Bar eye gene)? b.What kinds of crossovers produced the y v f b+ and v+ y+ f+ B offspring? Can you determine any genetic distances from these classed of progeny? c. What kinds of crossovers produced the…arrow_forward
- The mutant genes for vestigial wings and singed bristles are approximately 30 map units apart on chromosome II in Drosophila. Assume that a vestigial-winged female was mated to a singed-bristle male, and that the resulting F1 phenotypically wild type females were mated to vestigial singed males. Of 1000 offspring, which phenotype class would represent the product of crossing over between the genes, and how many would you expect? a) vestigial, 300 flies b) vestigial, 150 flies wild type, 300 flies d) singed, 150 flies e) vestigial, singed double mutants, 150 fliesarrow_forwardUsing Drosophila notation: A.) Diagram the genotype of a female fly that is recessive for apterus (ap, chromosome 2), heterozygous wild-type for black (b, chromosome 2), recessive for forked (f, x-chromosome), and homozygous wild type for rosy (ry, chromosome 3). B.) Diagram the genotype of a male fly that is heterozygous for clot (ct) eyes (an autosomal gene) and has yellow (y) body color (x-linked gene).arrow_forwardIn Drosophila, the genes ct(cut wing margin), y (yellow body), and v (vermilion eye color) are X-linked. Females heterozygous for all three markers were mated with wildtype males and the following male progeny were obtained. As is conventional in Drosophila genetics, the wild-type allele of each gene is designated by a “+” sign in the appropriate column. Use the data to (A) create a genetic map of the genes, (B) calculate interference, and (C) interpret the value of interference. Show your work.arrow_forward
- In drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. 1. What are the genotypes and phenotypes of the F2s? 2. If m-m- females produce useless eggs, then how are m-m- produced?arrow_forwardMale Drosophila from a true-breeding wild-type stock were irradiated with X-rays and then mated with females from a true-breeding stock carrying the following recessive mutations on the X chromosome: yellow body (y), crossveinless wings (cv), cut wings (ct), singed bristles (sn), and miniature wings (m). These markers are known to map in the order: Recessive alleles: y, cv, ct, sn, m Dominant alleles: y+, cv+, ct+, sn+, m+ y-cv-ct-sn-m у CV ct sn m X-rays х х X ct sn CV у m y+ CV+ ct+ sn+ m+ х X ? Exceptional female: Most of the female progeny of this cross were phenotypically wild type, but one female exhibited ct and sn mutant characteristics. When this exceptional ct sn female was mated with a male from the true-breeding wild-type stock, twice as many females as males appeared among the progeny. a. What is the nature of the X-ray-induced mutation present in the exceptional female? b. Draw the X chromosomes present in the exceptional ct sn female as they would appear during pairing…arrow_forwardIn drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? Show COMPLETE cross for both cases. If m-m- females produce useless eggs, then how are m-m- produced?arrow_forward
- One of the X chromosomes in a particular Drosophila female had a normal order of genes but carried recessive alleles of the genes for yellow body color (y), vermilion eye color (v), and forked bristles (f), as well as the dominant X-linked Bar eye mutation (B). Her other X chromosome carried the wild-type alleles of all four genes, but the region including y, v, and f (but not B) was inverted with respect to the normal order of genes. This female was crossed to a wild-type male as diagrammed here. 1. Draw the meiotic prophase I chromosomes with maximal pairing from the inversion heterozygous female. 2. (continued) When a crossover occurs between v and f, please draw the resulting chromosomes in four gametes.arrow_forwardThe genes for mahogany eyes and ebony body are approximately 18 map units apart on chromosome III in Drosophila. Assume that a mahogany-eyed female was mated to an ebony-bodied male, and the resulting F1 phenotypically wild-type females were mated to mahogany-ebony males. Of 942 offspring, what would be the expected phenotypes and in what numbers would they be expected?arrow_forwardFemale Drosophila heterozygous for three recessive mutations e (ebony body), st (scarlet eyes), and ss (spineless bristles) were testcrossed, and the following progeny were obtained: Phenotype Number wild-type 67 ebony 8 ebony, scarlet 68 ebony, spineless 347 ebony, scarlet, spineless 78 scarlet 368 scarlet, spineless 10 spineless 54 (a) What indicates that the genes are linked? (b) What was the genotype of the original heterozygous females? (c) What is the order of the genes? (d) What is the map distance between e and st? (e) Between e and ss? (f) What is the coefficient of coincidence? (g) Diagram the crosses in this experiment.arrow_forward
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