Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 45.3, Problem 2EQ
CoreSKILL » What was the hypothesis proposed by Evans in relation to PPAR-δ and obesity? How did Evans and his colleagues test this hypothesis, and what did they observe?
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What is NAGPRA? why is it important?
.Wheeler and Mathews (J. Biol. Chem. 286:16992–16996, 2011) reported
the concentrations of adenine nucleotides in rat liver mitochondria as fol-
lows: ATP, 5.5 mM; ADP, 5.1 mM; AMP, 1.8 mM.
(a) Calculate the adenylate energy charge within the mitochondrion
[ATP] + 0.5[ADP]
(adenylate energy charge
[ATP] + [ADP] + [AMPJ'
(b) Most measurements of adenylate energy charge in whole cells or
cytosol give values close to 0.9. Speculate on reasons why it might be
advantageous for mitochondria to have an ADP concentration almost as
high as that of ATP.
(c) succinyl-CoA + ADP + P¡
= -2.9 kJ/mol
If [P;] within the mitochondrion is 0.05 M and succinate and succinyl-
CoA are present at equimolar concentrations, what is the maximum
succinate + ATP + CoA-SH AG°'
mitochondrial concentration of CoA-SH at which the reaction can be
exergonic?
WHAT IF? If you measured ADH levels in patients with ADH receptormutations and in patients with aquaporin mutations, what would you expectto find, compared with wild-type subjects?
Chapter 45 Solutions
Biology
Ch. 45.1 - Prob. 1CCCh. 45.2 - Prob. 1CCCh. 45.2 - Prob. 1CSCh. 45.2 - Prob. 2CSCh. 45.3 - What is the normal function of the PPAR- protein...Ch. 45.3 - CoreSKILL What was the hypothesis proposed by...Ch. 45.3 - CoreSKILL Assume that the mean weight of both...Ch. 45 - Prob. 1TYCh. 45 - Prob. 2TYCh. 45 - Prob. 3TY
Ch. 45 - Prob. 4TYCh. 45 - The function of ATP during muscle contraction is...Ch. 45 - The function of Ca2+ in skeletal muscle...Ch. 45 - Stimulation of a muscle fiber by a motor neuron...Ch. 45 - Muscle fibers that have a large number of...Ch. 45 - Which of the following statements about movement...Ch. 45 - Prob. 10TYCh. 45 - Compare the structural and functional features of...Ch. 45 - Describe as many types of animal locomotion as you...Ch. 45 - Prob. 3CQCh. 45 - List and briefly describe the steps in the...Ch. 45 - Discuss the three types of muscle tissues found in...
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