The three types of muscle tissue in vertebrates are cardiac muscle, smooth muscle and skeletal muscle. The skeletal muscle is present throughout the body. It is directly involved in locomotion. It can generate action potentials in response to a stimulus. This results in an increased calcium ion concentration in the cytosol, which triggers force generation.

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Chapter 45, Problem 4TY

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Introduction: The three types of muscle tissue in vertebrates are cardiac muscle, smooth muscle and skeletal muscle. The skeletal muscle is present throughout the body. It is directly involved in locomotion. It can generate action potentials in response to a stimulus. This results in an increased calcium ion concentration in the cytosol, which triggers force generation.

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The functions of tropomyosin in skeletal muscle include A. releasing calcium ions after initiation of contraction. B. generating ATP which it passes to the contractile mechanism. C. binding to myosin during contraction. D. acting as a relaxing protein at rest by covering up the sites where myosin binds to actin. E. sliding on actin to produce shortening.

With regard to muscle contraction, which of the following is an INCORRECT statement with regard to the interactions of filaments that occur in the sarcomere? A. When muscles are relaxed tropomyosin blocks binding sites on actin subunits, which keeps cross-bridges from forming. B. The myosin heads conduct a power stroke motion to slide when bound to actin, to move the "thin" filaments towards the center of the sarcomere. C. During contraction, actin subunits are removed from the ends of the "thin" filaments to shorten actin polymers, thus reducing the length of the sarcomere. D. "Thick" filaments are anchored at the M-line, while "thin" filaments are anchored at the Z-line. E. Numerous myosin heads engage with the actin filaments simultaneously, such that there is no back-slipping during the contraction process.

Put the following skeletal muscle contraction events in the order that they occur: a. The myosin head swivels toward the center of the sarcomere. b. Calcium ions are released from the sarcoplasmic reticulum and bind to troponin. c. An action potential is propagated along the sarcolemma and transverse tubules. d. Myosin binds to actin, forming crossbridges. e. Myosin heads bind ATP molecules and release from actin. f. Tropomyosin molecules are moved off active sites on actin. g. ATPase splits ATP, providing the energy to reset the myosin head.