BIOLOGY
BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 44, Problem 4A
Summary Introduction

Introduction:

The hormones bind to their specific receptors in order to perform their functions. The binding of hormone-receptor may be altered by the presence of an antagonist, which binds to the receptor and blocks the activity of the hormone.

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A hormone signals through a G protein-coupled receptor as shown in the diagram. After the production of IP3, which of these events will MOST quickly stop the transduction of the signal? A. the hydrolysis of IP3 B. the hydrolysis of GTP C. the hydrolysis of PIP2 D. the hydrolysis of the hormone   I believe the answer is (B) the hydrolysisof GTP, because the G protein becomes inactive after GTP is hydrolyzed to GDP.  However, the solution provided by Bartleby is (C).  Please explain.  Thanks
Thyroid hormone receptor (TR) regulates growth, development, and differentiation of mammals. TR contains both a domain that binds to T3, the thyroid hormone, and a separate domain that binds to DNA. Which of the following BEST explains how TR signals?   A. T3 binds to TR at the cell membrane, which then releases second messengers to regulate gene expression.   B. T3 binds to DNA at the cell membrane, which then releases second messengers to regulate gene expression.   C. T3 diffuses through the cell membrane to bind to TR, which then binds to DNA to regulate gene expression.   D. T3 diffuses through the cell membrane to bind to DNA, which then binds to TR to regulate gene expression.
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