Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Textbook Question
Chapter 44, Problem 44.5CR
Why can only some patients with diabetes insipidus be treated effectively with ADH?
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Why can only some patients with diabetes insipidus be treated effectively with ADH?
Which of the following best describes the role of the hexosamine pathway in the pathogenesis of the chronic complications of diabetes mellitus?
Question 79 options:
a)
It involves irreversible binding of glucose to proteins, lipids and nucleic acids which damages components of the microcirculation leading to retinopathy, etc.
b)
It promotes the O-linked glycosylation of proteins and transcription factors, resulting in altered gene expression contributing to insulin resistance & cardiovascular complications
c)
It promotes the synthesis of DAG which increases pro-inflammatory gene expression and endothelial ET-1 production resulting in blood flow abnormalities
d)
It leads to intracellular accumulation of osmotically active sorbitol and fructose which damages Schwann cells, erythrocytes and the lens of the eye
Diabetes insipidus has been identified in two males. One person did not have the condition until he had a stroke. The other had lived with the condition his whole life, and despite the existence of normal ADH receptors, it had never reacted to exogenous ADH. What might be the cause of the two men's diabetes insipidus? Provide your references.
Chapter 44 Solutions
Campbell Biology
Ch. 44.1 - The movement of salt from the surrounding water to...Ch. 44.1 - Prob. 2CCCh. 44.1 - WHAT IF? Researchers found that a camel in the...Ch. 44.2 - What advantage does uric acid offer as a...Ch. 44.2 - Prob. 2CCCh. 44.3 - Prob. 1CCCh. 44.3 - Where and how does filtrate originate in the...Ch. 44.3 - Prob. 3CCCh. 44.4 - What do the number and length of nephrons in a...Ch. 44.4 - Many medications make the epithelium of the...
Ch. 44.4 - Prob. 3CCCh. 44.5 - How does alcohol affect regulation of water...Ch. 44.5 - Prob. 2CCCh. 44.5 - Prob. 3CCCh. 44 - Prob. 44.1CRCh. 44 - DRAW IT Construct a table summarizing the three...Ch. 44 - Prob. 44.3CRCh. 44 - Prob. 44.4CRCh. 44 - Why can only some patients with diabetes insipidus...Ch. 44 - Prob. 1TYUCh. 44 - Prob. 2TYUCh. 44 - Prob. 3TYUCh. 44 - Prob. 4TYUCh. 44 - In which of the following species should natural...Ch. 44 - Prob. 6TYUCh. 44 - Prob. 7TYUCh. 44 - Prob. 8TYUCh. 44 - SCIENTIFIC INQUIRY You are exploring kidney...Ch. 44 - Prob. 10TYUCh. 44 - SYNTHESIZE YOUR KNOWLEDGE The marine iguana...
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- Explain the difference between type 1 and type 2 diabetesmellitus.arrow_forwardWhich of the following describes a feature of the pathophysiology of type 2 diabetes? Question 15 options: a) It is usually an autoimmune disease b) The pancreas makes little or no insulin c) Diabetic ketoacidosis is a common complication d) The liver increases production of glucosearrow_forwardWhich of the following statements about type 1 diabetes pathophysiology are true? Select all that apply A) The immune system begins to attack pancreatic B-cells in response to elevated blood sugar B) The activated immune system destroys pancreatic ß cells C) Thelper cells are activated resulting in production of autoantibodies from self-reactive plasma cells D) The body does not produce self-reactive cytotoxic T cellsarrow_forward
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