Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 4, Problem 28RQ
Summary Introduction
To explain: The number of amino acids in a polypeptide that is translated from a protein-coding sequence of mRNA having 450 bases.
Introduction: A codon is a set of three nucleotides that codes for a particular amino acid. There are four different nucleotides in molecules of DNA and RNA. These nucleotides are assembled to give codons, and in total, 64 different codons are possible.
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Students have asked these similar questions
If there are 64 possible codons in the genetic code and the amino acid is specified by each, as read in the 5’ to 3’ direction from the mRNA sequence, which ones are STOP codons?
The following RNA sequence represents a small messenger which can be translated in a prokaryotic cell:
5'-ACGAAUGCACAGUAAAACUGGCUAGCGUAGGCUGA-3
Assume that the messenger RNA is translated in the cell, using the correct machinery and signals
required for accurate protein synthesis. Using this RNA sequence and the Genetic Code Dictionary (see
your textbook for the dictionary), solve the following problems
A. Write the sequence of a protein that would be translated from this mRNA, using the appropriate stop and start
signals, and indicating the correct termini of the protein product.
B. Suppose that the underlined A in the sequence is changed to a U. Write the expected protein product of this
mRNA.
Assume the following portion of an mRNA. Find a start signal, and
write the amino acid sequence that is coded for.
5'-GCCAUGUUUCCGAGUUAUCCCAAAGAUAAAAAAGAG 3'
Chapter 4 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 4.1 - Which biomolecules always include nitrogen in...Ch. 4.1 - Prob. 2CCCh. 4.1 - What is the difference between potential energy...Ch. 4.1 - Prob. 4CCCh. 4.2 - Prob. 5CCCh. 4.2 - Prob. 6CCCh. 4.2 - Prob. 7CCCh. 4.3 - Prob. 8CCCh. 4.3 - Prob. 9CCCh. 4.3 - Prob. 10CC
Ch. 4.3 - Prob. 11CCCh. 4.4 - Name five ways in which cells regulate the...Ch. 4.4 - Prob. 13CCCh. 4.4 - Prob. 14CCCh. 4.4 - Match each component on the left to the...Ch. 4.4 - Prob. 16CCCh. 4.4 - How is the separation of mitochondria into two...Ch. 4.4 - Prob. 18CCCh. 4.4 - Prob. 19CCCh. 4.4 - Prob. 20CCCh. 4.4 - What does the name RNA polymerase tell you about...Ch. 4.4 - Explain in one or two sentences the relationship...Ch. 4.4 - Prob. 23CCCh. 4.4 - List three general types of posttranslational...Ch. 4.4 - Prob. 25CCCh. 4 - List the three basic forms of work and give a...Ch. 4 - Prob. 2RQCh. 4 - Prob. 3RQCh. 4 - Prob. 4RQCh. 4 - Prob. 5RQCh. 4 - Prob. 6RQCh. 4 - Match each definition in the left column with the...Ch. 4 - Prob. 8RQCh. 4 - Organic molecules that must be present in order...Ch. 4 - In an oxidation-reduction reaction, in which...Ch. 4 - Prob. 11RQCh. 4 - Prob. 12RQCh. 4 - Prob. 13RQCh. 4 - Metabolic regulation in which the last product of...Ch. 4 - Prob. 15RQCh. 4 - Prob. 16RQCh. 4 - Create maps using the following terms.Ch. 4 - Prob. 18RQCh. 4 - Prob. 19RQCh. 4 - Prob. 20RQCh. 4 - Prob. 21RQCh. 4 - Briefly describe the processes of transcription...Ch. 4 - On what molecule does the anticodon appear?...Ch. 4 - Is the energy of ATPs phosphate bond an example of...Ch. 4 - Prob. 25RQCh. 4 - Prob. 26RQCh. 4 - Prob. 27RQCh. 4 - Prob. 28RQ
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- How many different mRNA sequences can encode a polypeptide chain with the amino acid sequence Met-Leu-Arg? (Be sure to include the stop codon.)arrow_forwarddraw mRNA sequence for the following sequence ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGACCCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTACCTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGACCTGCAGGTGGGGCAGGTGGAGCTGGGCGGGGGCCCTGGTGCAGGCAGCCTGCAGCCCTTGGCCCTGGAGGGGTCCCTGCAGAAGCGTGGCATTGTGGAACAATGCTGTACCAGCATCTGCTCCCTCTACCAGCTGGAGAACTACTGCAACTAGarrow_forwardIndicate the amino acid sequence of the protein encoded by the following mRNA molecule. Use the genetic code table and assume that the very first “AUG” the ribosome encounters will serve as the start codon and specify methionine. 5’-AAUUCAUGCCCAAAUUUGGGGCACGAAGCUUCUUAGGCUAGUCCUAAAAAA-3’arrow_forward
- Using the codon given for each amino acid (Find the table yourself) write the base sequence of mRNA that would translate the synthesis of the following pentapeptide:Arg · Ile · Cys · Tyr · Valarrow_forwardDetermine the amino acid sequence for a polypeptide coded for by the following mRNA transcript (written 5'-> 3'): AUGCCUGACUUUAAGUAGarrow_forwardUsing the genetic code table provided below, write out the sequence of three different possible mRNA sequences that could encode the following sequence of amino acids: Met-Phe-Cys-Trp-Glu C A G U C UUU Phe UCU Ser UUC Phe UCC Ser UCA Ser UUA Leu UUG Leu UCG Ser CUU Leu CCU Pro CUC Leu CUA Leu CUG Leu CCG A CAU His CGU Arg CCC Pro CAC His CGC Arg UAU Tyr UGU Cys U UAC Tyr UGC Cys C Stop UGA Stop Stop UGG Trp UAA A UAG G CCA Pro CAA Gln Pro CAG AUU lle AUC lle AUA lle AUG Met ACG G 등등 Gln CGA Arg CGG Arg ACU Thr AAU Asn AGU Ser ACC AAC Asn AGC Ser Thr ACA Thr Thr AAA Lys AGA Arg AAG Lys AGG Arg GUU Val GCU Ala GAU Asp GGU Gly GGC Gly GUC Val GCC Ala GAC Asp GUA Val GCA Ala GAA Glu GGA Gly GUG Val GCG Ala GAG Glu GGG Gly U C A G U C A G SUAUarrow_forward
- Translation is the process by which the sets of 3 bases (codons) of the mRNA are read to specify the sequence of amino acids for the protein to be produced. Using the genetic code data provided, find the sequence of amino acids that would correspond to the MRNA codons shown. Codons 1 3 MRNA A UGUGGAUC CGAG UCACG Amino acid SECOND LETTER A U UUU Phenylalanine UCU UCC Serine (S) UAU Tyrosine (Y) UAC TAA stop codon UAG stop codon UGU Cysteine (C) UGC TỮA Leucine (L) TGA stop codon UGG Tryptophan (W) F UCA UUG UCG I H CUU CCU CAU Histidine (H) R CGU CỨC Leucine (L) CỦA CCC Proline (P) ССА CCG CGC Arginine (R) CGA CAC "CAA Glutamine CAG (Q CUG CGG G D A AUU L AUC Isoleucine (1) AAU Asparagine AAC (N) ÄÄÄ Lysine (K) AGU Senine (S) ACU ACC Threonine ACA (T) AGC E AUA AGA Arginine (R) E ACG T AUG stat codon (M) AAG AGG TG GƯỮ GAU Apartic acid GAC (D) "GAÄ Glutamic acid GCU GGU GUC Valine (V) GUA GGC Glycine (0) GCC Alanine (A) CE GCA GGA R GUG GCG GGG GAG (E) The start codonencodes the amino…arrow_forwardWhat is the total size of the mature i.e. fully processed mRNA in nucleotides? How many amino acids would the encoded protein be? Assume that the N- terminal Met encoded by the AUG start codon, is NOT cleaved from the protein?arrow_forwardFor the following mRNA sequences, what is the amino acid sequence formed? Consult genetic code table for reference. 5' AGUCCGUAC 3' 5' AAUUGCUUC 3'arrow_forward
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