Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Chapter 32.4, Problem 6CC
Discuss the role of NK cells in protecting the host. What are the two mechanisms NK cells use to detect altered cells?
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Cancer cells evade immune surveillance. What "strategies" can cancer cells use to escape NK cells?
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** SELECT ALL THAT APPLY ** Which of the following statements are correct regarding NK cells?
a)they are present in the blood and lymph.
b) they are highly phagocytic macrophages .
c) their activation tequires co-stimulation.
d) they attack cells that display abnormal MHC antigens.
Chapter 32 Solutions
Prescott's Microbiology
Ch. 32.1 - Prob. 1CCCh. 32.1 - Prob. 2CCCh. 32.2 - Why is the skin such a good first line of defense...Ch. 32.2 - Prob. 2CCCh. 32.3 - What strategies could a Gram-negative bacterium...Ch. 32.3 - Prob. 1CCCh. 32.3 - Prob. 2CCCh. 32.3 - Prob. 3CCCh. 32.3 - Prob. 4CCCh. 32.3 - Prob. 5CC
Ch. 32.3 - Prob. 6CCCh. 32.3 - Prob. 7CCCh. 32.4 - Prob. 1MICh. 32.4 - Describe the structure and function of each of the...Ch. 32.4 - Prob. 2CCCh. 32.4 - Prob. 3CCCh. 32.4 - Prob. 4CCCh. 32.4 - Prob. 5CCCh. 32.4 - Discuss the role of NK cells in protecting the...Ch. 32.5 - Prob. 1MICh. 32.5 - Prob. 1CCCh. 32.5 - Injury to the spleen can lead to its removal. What...Ch. 32.5 - Describe SALT and MALT functions in innate...Ch. 32.6 - Prob. 1CCCh. 32.6 - Prob. 2CCCh. 32.6 - Prob. 3CCCh. 32.7 - Prob. 1MICh. 32.7 - Prob. 1CCCh. 32.7 - Prob. 2CCCh. 32 - Prob. 1RCCh. 32 - Prob. 2RCCh. 32 - Prob. 1ALCh. 32 - Prob. 2ALCh. 32 - Prob. 3ALCh. 32 - Prob. 4AL
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A flu-infected cell has down-regulated its MHC class I expression. The lymphocytes below comes to the site and interacts with the cell. How does the downregulation of MHC class I affect these ability of lymphocytes to kill the infected cell? a) influenza-specific T cell b) NK cell c) herpes-specific T cell Indicate whether the possibility increases, decreases or is unchanged for each cell.arrow_forwardName two antigen-presenting cells. What is their role in the adaptive immune system? Which classes of MHC proteins do they express and why is this important?arrow_forwardDistinguish between the innate and adaptive immune systems in terms of cell types used, how they recognize pathogens, and how they protect animals from infection. Predict how perturbations in immune cells or immune responses influence innate immune system function. Predict how perturbations in immune cells or immune responses influence adaptive immune system function. Explain how traditional and mRNA vaccines work using the terms: antibody, antigen, B-cells, helper T-cells, plasma cells, and memory B-cells. Predict whether an infection or perturbations in B- and T- cell development might predispose someone to develop an autoimmune disease.arrow_forward
- What is the activation signal for NK cells? How doesthis differ from the activity of T-cytotoxic lymphocytes?arrow_forwardOpsonization of pathogens by both antibodies and complement proteins (C3b) leads to uptake and destruction of the pathogen by phagocytic cells that express both Fc receptors and complement receptors. Which of the following in the figure below is the most efficient form of dual opsonization of the pathogen by antibody and C3b to maximize phagocytosis?arrow_forwardExplain the mechanism by which NK cells are able to engage a highly specific antigen receptor during their activation.arrow_forward
- Describe the roles that phagocytic and nonphagocytic cells and plasma proteins such as complement and interferon play in innate immunity?arrow_forwardName two ways in which the presence of antibodies enhances phagocytosis.arrow_forwardCompare B cell receptors and T cell receptors for the following criteria: BCR TCR Tyrosine kinases Adaptors and scaffold proteins Phospholipases and lipid kinases GTPases, serine/threonine kinases and phosphatases Transcription factors, cytoskeletal changes, adhesion, metabolismarrow_forward
- Discuss three mechanism by which antibody mediate the destruction of pathogen.arrow_forwardDescribe the term "in-frame" and also the reason that it would be necessary for the generation of diversity in antigen receptors.arrow_forwardThe innate immune response together with antibodies are generally not effective at clearing infections established by pathogens that replicate inside host cells. The evolution of T cells has provided a means for the immune response to ‘see’ intracellular infections based on the ability of T cells to: Secrete cytokines that diffuse into the infected tissue Activate type I interferon production by macrophages and dendritic cells Activate macrophages to induce inflammation Recognize pathogen-derived peptides on host MHC surface molecules Express cytoplasmic sensors for detecting pathogen-derived nucleic acidsarrow_forward
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