Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 3, Problem 2CS
If you were in Thomas’s position, would you want to be tested and possibly learn that you were almost certain to develop the disorder sometime in the next 5–10 years?
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The father of three sons and two daughters begins to show symptoms of Huntington's disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?
What would be the phenotypes for each of the following genotypes for Huntington’s Disease?
a. Hh =
b. hh =
The father of five children begins to show symptoms of huntington disease. what is the probability that same, the man's second oldest son (11-2),, will suffer from the disease if he lives a normal life span? Sam's mother and her ancestors do not have the diseas. Sam's father was adopted, so we do not know his biological family history for hunutington disease. Explore all possible outcome for sam and explain your reasoning
Chapter 3 Solutions
Concepts of Genetics (12th Edition)
Ch. 3 - Pigeons may exhibit a checkered or plain color...Ch. 3 - Considering the Mendelian traits round versus...Ch. 3 - Using the forked-line, or branch diagram, method,...Ch. 3 - In one of Mendels dihybrid crosses, he observed...Ch. 3 - The following pedigree is for myopia...Ch. 3 - If they seek genetic counseling, what issues would...Ch. 3 - If you were in Thomass position, would you want to...Ch. 3 - If Thomas tests positive for the HD allele, should...Ch. 3 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 3 - CONCEPT QUESTION Review the Chapter Concepts list...
Ch. 3 - Albinism in humans is inherited as a simple...Ch. 3 - Which of Mendels postulates are illustrated by the...Ch. 3 - Discuss how Mendels monohybrid results served as...Ch. 3 - What advantages were provided by Mendels choice of...Ch. 3 - Mendel crossed peas having round seeds and yellow...Ch. 3 - Based on the preceding cross, what is the...Ch. 3 - Which of Mendels postulates can only be...Ch. 3 - In a cross between a black and a white guinea pig,...Ch. 3 - What is the basis for homology among chromosomes?Ch. 3 - In Drosophila, gray body color is dominant to...Ch. 3 - How many different types of gametes can be formed...Ch. 3 - Mendel crossed peas having green seeds with peas...Ch. 3 - In a study of black guinea pigs and white guinea...Ch. 3 - Mendel crossed peas having round green seeds with...Ch. 3 - Prob. 17PDQCh. 3 - The following are F2 results of two of Mendels...Ch. 3 - In assessing data that fell into two phenotypic...Ch. 3 - Prob. 20PDQCh. 3 - Consider the following pedigree. Predict the mode...Ch. 3 - Draw all possible conclusions concerning the mode...Ch. 3 - For decades scientists have been perplexed by...Ch. 3 - A wrongful birth case was recently brought before...Ch. 3 - TaySachs disease (TSD) is an inborn error of...Ch. 3 - Datura stramonium (the Jimsonweed) expresses...Ch. 3 - The wild-type (normal) fruit fly, Drosophila...Ch. 3 - To assess Mendels law of segregation using...Ch. 3 - Albinism, caused by a mutational disruption in...Ch. 3 - (a) Assuming that Migaloos albinism is caused by a...
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- If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this an indication that there is a genetic contribution to these traits? What would you do to confirm that genetics is involved in this condition?arrow_forwardA woman who is eight (8) weeks pregnant requests a direct test for Huntington’s disease on her fetus. She tells her geneticist that she wants the test because she recently discovered that there is a family history of the disease in her husband’s family. One of his parents is affected so he is at 50% risk of developing the condition. She is adamant that she does not want to give birth to a baby who is at risk of developing Huntington’s and says that the test will help her to ensure that this is not the case. In counseling, she reveals that she has discussed this issue several times with her husband but he has always said he is not willing to take a test. He does not want to know his status and is extremely anxious about the possibility that he might develop the condition. The woman and her husband are currently separated but are seeing a relationship counselor and trying to work things out. Despite this, the woman says they tend to fight a lot. When it is explained to her in counseling…arrow_forwardBelow you may find the pedigree diagram for a family with two boys having childhood onset epileptic encephalopathy. Please indicate 4 different inheritance models and state your reasons briefly for this disorder by considering the pedigree.arrow_forward
- Monozygotic twins: Question 2 options: a) Share 50% of their genetic material and if one twin has schizophrenia the risk of the other having the illness if 40-50% b) Share 100% of their genetic material and if one twin has schizophrenia, the risk of the other having schizophrenia is 10-15% c) Share 100% of their genetic material and if one twin has schizophrenia, the risk of the other having schizophrenia is 40-50% d) Share 50% of their genetic material and if one twin has schizophrenia the risk of the other having the illness is 10-15%arrow_forwardWhat are newest advances in early diagnosis and confirmation of Huntington disease? Explain the difference in inheritance pattern and the frequency to have affected progeny in the case of these three inherited diseases: Huntington, Cystic fibrosis and Duchenne muscular dystrophy. What therapies can be used or recommended for patients experiencing any of these inherited diseases?arrow_forwardIf both parents carry one copy each of the mutation that causes Huntingtons , what are the odds that their child would have the disease ? A)25 B 75 C 50 D 100arrow_forward
- A woman diagnosed with Alzheimer disease wants to know the probability that her children will inherit the disorder. Explain to her the complications of determining heritability for this disease.arrow_forwardinterpret using the punnett square below to both sets of parents (Parents A , Parents B, & Parents C).based on your results of filling in the boxes. What are the chances Parents A, Parents B, and Parents C will have a child with Sickle Cell? What are the chances the child will be a carrier for Sickle Cell?arrow_forwardCystic fibrosis (CF) is an autosomal recessive trait (a). Assume that Emily (who has CF) decides to have children with a man who does not have CF and who is not a carrier of CF. What are their genotypes, and what is the probability that they will have a child who is a carrier for CF?arrow_forward
- Huntington’s Disease is a dominant lethal disease that manifests later in life after many people have had children. If you were the child of a parent who was diagnosed with Huntington's, would you want to be tested for the condition? Why or why not?arrow_forwardYou met with two parents whose first child has sickle cell anemia. (The parents show no signs of the disease themselves). The mother comes to you in the third month of her second pregnancy, and wants to know if this child will also inherit the disease. As a genetics counselor, you are ready to evaluate this couple’s case by doing the following:1. Determine what the genotype of each parent is. Is this disease autosomal or sex-linked? Dominant or recessive?arrow_forwardHow is this disorder inherited? State your reasoningarrow_forward
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