Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 28, Problem 10P
Interpretation Introduction
Interpretation:
The potential difficulties in treating sleeping sickness should be determined.
Concept introduction:
Sleeping sickness is a tropical disease which is caused by
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ILLUSTRATIONS. For each of the given proteins:
Draw the final location of the following proteins after being translocated.
•
Label the organelle (as well as the organelle parts/compartments) and the cytosol (if necessary) in order
to clearly depict the protein's location and orientation.
•
Label the amino and carboxyl ends of the protein.
Below your drawing, indicate:
a. the receptor/s
b. the energy source
c. if there is signal peptide cleavage or none
A. Peroxisome: Class I PMP
H₂N-
ITS*
*Internal targeting sequence
-COOH
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