LooseLeaf for Human Anatomy
LooseLeaf for Human Anatomy
5th Edition
ISBN: 9781259285271
Author: Michael McKinley Dr., Valerie O'Loughlin, Elizabeth Pennefather-O'Brien
Publisher: McGraw-Hill Education
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Chapter 27, Problem 3CR
Summary Introduction

To determine:

The flow of blood into and out of the kidney and mention the structures that carry oxygenated and deoxygenated blood. List the structures that help in the reabsorption of materials and gas exchange.

Introduction:

Kidneys are paired bean-shaped organs present in the left and right retroperitoneal space. The kidney contains millions of nephrons. The nephron is the filtration unit of the kidney.

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Explain the role of renin-angiotensin - aldosterone pathway in restoring blood pressure and fluid balance.  Include the stimulus for release, the pathway that is involved,  and the physiological effects of angiotensin II and aldosterone.   Answer should include: Identify stimulus/change that starts the pathway (i.e. Identify the direction of change IN BP or circulating fluid status) What happens in the juxtaglomerular cells? Clue: what stimulus causes the release of renin? Explain action of renin - what protein does it act on? What is it converted to? Which enzymes converts angiotensin 1 to angiotensin 2? What are the actions of angiotensin 2? Clue: stimulates adrenal context to produce what? And what effect does angiotensin 2 have on blood vessels? What causes reabsorption of Na into blood ? What effect does this have on blood volume? How is BP restored ? Explain how this relates to equation for BP ( BP= CO x TPR)
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