Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Textbook Question
Chapter 26, Problem 26.5CC
Patients who have received organ transplants typically receive immunosuppressant drugs. Such patients also have an increased risk of developing solid tumors and cancers of the blood. Explain this result.
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The transplantation of organs from one person to another was impossible until the discovery of immunosuppressive drugs. Now, with the use of drugs such as cyclosporine, organs can be transplanted without rejection. Transplant patients must take immunosuppressive drugs for the remainder of their lives. What are the potential risks associated with long-term use of immunosuppressive drugs?
Explain the term immunoglobulin (IG).
Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Explain relevant concepts in relation to tissue rejection in organ transplant.
Chapter 26 Solutions
Becker's World of the Cell (9th Edition)
Ch. 26 - As you will learn later in this chapter, cancer...Ch. 26 - Prob. 26.2CCCh. 26 - Although tobacco smoking is responsible for a...Ch. 26 - Prob. 26.4CCCh. 26 - Monoclonal antibodies directed against the CD20...Ch. 26 - Patients who have received organ transplants...Ch. 26 - Prob. 26.1PSCh. 26 - Phorbol Esters and Cancer. The active ingredient...Ch. 26 - Angiogenesis. Describe two pieces of evidence...Ch. 26 - Prob. 26.4PS
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- In local inflammation, the vasodilation of blood vessels in the area of infection is the result of the release of _____. Group of answer choices tumor necrosis factor histamine leukotrienes prostaglandin E2arrow_forwardVaccines are used to train our adaptive immune system. With live-attenuated vaccines, a weakened form of the pathogen is injected. Describe the steps of an adaptive immune response to this type of vaccine (1 sentence per step). Explain how the immune system of a person who received the vaccine would respond to a later exposure to the pathogen (1-2 sentences).arrow_forwardExplain why it would be important for a person living with AIDS or for someone who has recently received radiation therapy to avoid people with a cough or cold?arrow_forward
- HIV predominantly infects T-helper cells, cells that are responsible for coordinating B- and T-cell activity. Based on this information, explain why HIV-infected individuals are at a very high risk for developing microbial infections. List the causative agent (virus) and discuss its properties. Name and briefly discuss 3 diseases that AIDS patients are more likely to contract.(Terminology to use: opportunistic pathogens, T and B cell purposes, CD4 cells, retrovirus, reverse transcription)arrow_forwardExplain why Kaposi’s sarcoma is more common inimmunocompromised patients.arrow_forwardPatients who have recently had a bone marrow transplant are extremely susceptible to infection. Why would this be so?arrow_forward
- Explain why immunosuppressive drugs should be taken on aregular and permanent basis following a transplant.arrow_forwardIn HIV, helper T cells are affected. Describe how this impacts both the humoral and cell- mediated immune system. Why would an ordinary cold virus be dangerous to an AIDS patient?arrow_forwardA 39-year-old woman with rheumatoid arthritis comes to the physician for a follow-up examination. Treatment with multiple medications, including prednisone and methotrexate, has not been effective at slowing the progress of her condition. The most appropriate next step in pharmacotherapy is a drug that blocks the effects of which of the following cytokines? Entaracept : Fusion protein- decoy receptor A) Interferon gamma B) Interleukin-2 (IL-2) C) IL-4 D) IL-10 E) Tumor necrosis factor-a foundarrow_forward
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