Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 26, Problem 22E
Summary Introduction

To draw: A diagram including exons and introns of a gene that encodes both membrane-bound and soluble forms of a protein.

Introduction: In eukaryotes, transcription occurs in the nucleus, and pre-mRNA is synthesized. This pre-mRNA is further modified before translation in the cytoplasm. This is known as RNA processing. It includes the modification of mRNA ends and RNA splicing. During RNA splicing, the non-coding regions, that is introns, are excised from the RNA molecules, and the coding regions are joined.

Summary Introduction

To explain: How one gene can code for two different forms of a protein.

Introduction: In eukaryotes, transcription occurs in the nucleus, and pre-mRNA is synthesized. This pre-mRNA is further modified before translation in the cytoplasm. This is known as RNA processing. It includes the modification of mRNA ends and RNA splicing. During RNA splicing, the non-coding regions, that is introns, are excised from the RNA molecules, and the coding regions are joined. Some genes undergo alternative splicing, which leads to the production of two or more different mRNAs from the same primary transcript.

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