Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 26, Problem 10P
Interpretation Introduction
Interpretation:
A balanced equation for the conversion of asparate to fumarate by the purine nucleoside cycle in skeletal muscle.
Concept introduction:
The conversion of IMP to AMP may be a transamination reaction during which IMP is a keto acceptor.
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The mitochondrial form of carbamoyl phosphate synthetase is allosterically activated by N-acetylglutamate. Briefly describe a rationale for this effect.
Intramitochondrial ATP concentrations are about 5 mM, and phosphate
concentration is about 10 mM. If ADP is five times more abundant than
AMP, calculate the molar concentrations of ADP and AMP at an energy
charge of 0.85. Calculate AG for ATP hydrolysis at 37 °C under these condi-
tions. The energy charge is the concentration of ATP plus half the concen-
tration of ADP divided by the total adenine nucleotide concentration:
[ATP] + 1/2[ADP]
[ATP] + [ADP] + [AMP]
The allosteric properties of aspartate transcarbamoylase have been discussed in detail in this chapter. What is the function of aspartate transcarbamoylase?
Chapter 26 Solutions
Biochemistry
Ch. 26 - Prob. 1PCh. 26 - Prob. 2PCh. 26 - Allosteric Regulation of Purine and Pyrimidine...Ch. 26 - Inhibition of Purine and Pyrimidine Metabolism by...Ch. 26 - Prob. 5PCh. 26 - Allosteric Regulation of Ribonucleotide Reductase...Ch. 26 - Prob. 7PCh. 26 - Prob. 8PCh. 26 - Prob. 9PCh. 26 - Prob. 10P
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