Human Anatomy & Physiology (2nd Edition)
2nd Edition
ISBN: 9780134553511
Author: Erin C. Amerman
Publisher: PEARSON
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Textbook Question
Chapter 24.5, Problem 2QC
What are the three types of transport processes that involve carrier proteins in the renal tubule and collecting system?
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The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations.
For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion
Explain how you determined this.
What is an example of a diagram that explains the core concept of flow down gradients in the urinary system/kidneys?
What are the two intrinsic mechanisms that provide auto regulation of glomerular filtrate? Explain any one of these.
Chapter 24 Solutions
Human Anatomy & Physiology (2nd Edition)
Ch. 24.1 - What are the organs of the urinary system?Ch. 24.1 - 2. What are the basic functions of the kidneys?
Ch. 24.2 - Prob. 1QCCh. 24.2 - 2. What are the three regions of the kidney, and...Ch. 24.2 - Prob. 3QCCh. 24.2 - Trace the sequence of blood flow through the...Ch. 24.2 - Prob. 5QCCh. 24.2 - Prob. 6QCCh. 24.2 - Trace the pathway filtrate takes through the...Ch. 24.3 - Prob. 1QC
Ch. 24.3 - 2. How do tubular reabsorption and tubular...Ch. 24.4 - Prob. 1QCCh. 24.4 - Prob. 2QCCh. 24.4 - Prob. 3QCCh. 24.4 - 4. What is the GFR?
Ch. 24.4 - Prob. 5QCCh. 24.4 - Prob. 6QCCh. 24.4 - 7. How does tubuloglomerular feedback affect the...Ch. 24.4 - Prob. 8QCCh. 24.4 - Prob. 9QCCh. 24.4 - Prob. 10QCCh. 24.4 - How does the sympathetic nervous system affect the...Ch. 24.5 - Prob. 1QCCh. 24.5 - 2. What are the three types of transport...Ch. 24.5 - Prob. 3QCCh. 24.5 - What is obligatory water reabsorption?Ch. 24.5 - How do the permeabilities of the two limbs of the...Ch. 24.5 - Prob. 6QCCh. 24.5 - Prob. 7QCCh. 24.5 - Prob. 8QCCh. 24.6 - Prob. 1QCCh. 24.6 - Prob. 2QCCh. 24.6 - Prob. 3QCCh. 24.6 - Prob. 4QCCh. 24.6 - 5. What three factors allow the kidney to produce...Ch. 24.6 - 6. How is concentrated urine produced?
Ch. 24.8 - 1. What is the normal composition of urine?
Ch. 24.8 - Prob. 2QCCh. 24.8 - 3. What is renal clearance, and what is it used...Ch. 24.9 - Prob. 1QCCh. 24.9 - 2. What are the functions of the ureters and...Ch. 24.9 - Prob. 3QCCh. 24.9 - Prob. 4QCCh. 24.9 - Prob. 5QCCh. 24 - What are the four main organs of the urinary...Ch. 24 - 2. Which of the following is not a physiological...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Prob. 4CYRCh. 24 - Prob. 5CYRCh. 24 - Which of the following substances would pass...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Fill in the blanks for the following statements:...Ch. 24 - Which of the following is false about the GFR? a....Ch. 24 - The route by which substances are reabsorbed by...Ch. 24 - 11. Fill in the blanks: Glomerular hydrostatic...Ch. 24 - Dilute urine is produced when decreased levels of...Ch. 24 - Prob. 13CYRCh. 24 - Prob. 14CYRCh. 24 - Prob. 15CYRCh. 24 - 16. The GFR may be estimated by measuring the rate...Ch. 24 - Prob. 17CYRCh. 24 - Prob. 1CYUCh. 24 - Prob. 2CYUCh. 24 - Prob. 3CYUCh. 24 - Why must the kidneys establish a concentration...Ch. 24 - 1. Drugs that treat hypertension, or high blood...Ch. 24 - Prob. 2AYKACh. 24 - 3. Deana is a 4-year-old girl with a rare genetic...Ch. 24 - 4. Explain how each of the drugs in question 1...Ch. 24 - 5. What might it mean if you found a high...
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- One type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle. A) What does it mean to inhibit the transport of sodium ions in the loop of Henle? B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.arrow_forwardWhat are the physiological implications of excreting waste nitrogen in the form of urate, urea, or ammonia?arrow_forwardDraw a schematic diagram showing the flow of water and salts in the proximal tubule of the kidney. In this diagram, put the lumen on the left side of the diagram and the extracellular fluids on the right side of the diagram. Indicate where the lumen is, where the extracellular fluid is, where the apical portion of the cell is, and show the location of the proteins that are responsible for the movement of water and salts and glucose reabsorption in this area of the kidneyarrow_forward
- How does a) the volume b) Na + conc & c) the osmolality of the filtrate in the different regions of the nephron change?arrow_forwardEpithelial cells that reabsorb solutes are cuboidal, but epithelial cells involved in filtration are thin, squamous cells. The cuboidal cells contain more cytoplasm and organelles, especially mitochondria and rough endoplasmic reticulum (RER), than the squamous cells. Why do the cuboidal cells of the kidney tubules need more mitochondria and RER?arrow_forwardGlomerular filtration is affected by forces that oppose and promote filtration. What are these forces and explain the theory behind net filtration pressure?arrow_forward
- On what side of the renal tubule cell does active transporttake place during reabsorption of materials?arrow_forwardWhat is the transport maximum of a substance? How is it different from the renal threshold of the substance?arrow_forwardThe presence of either protein or glucose in a urinalysis is abnormal, but these two molecules end up in the urine for different reasons. For each of these molecules, briefly describe where in the urine production process (i.e., glomerular filtration, tubular reabsorption or tubular secretion) the problem occurs, and why it might happen.arrow_forward
- The process of hydrogen ion secretion in the proximal convoluted tubule occurs via which of the following mechanisms? Choose from the following: (A) hydrogen ions diffuse out of the glomerular filtrate of the proximal convoluted tubule, through extracellular fluid and into the peritubular blood (B) carbon dioxide diffuses into the proximal convoluted tubule cell from peritubular capillary blood; undergoes a chemical reaction to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ion diffuses into the glomerular filtrate of the proximal convoluted tubule (C) hydrogen ions diffuse out of the peritubular capillary blood, through extracellular fluid and into the filtrate of the proximal convoluted tubule (D) carbon dioxide diffuses into the proximal convoluted tubule cell from the glomerular filtrate; undergoes a chemical reacdtion to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ions diffuse into the peritubular bloodarrow_forwardCompare the processes of reabsorption and secretion in terms of transporters involved. Is all reabsorption and/or secretion in the kidneys an active process?arrow_forwarda)Name the two factors that trigger the release of ADH (vasopressin). b) What happens to plasma osmolarity when there is excessive water loss through sweating and it is not replaced? c) Describe the renal regulation of potassium, where is K+, what is the hormone that is responsible for the secretion of K+, the name of the cells, and the location in the nephron where the fine-tuning of K+ occurs.arrow_forward
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