Prescott's Microbiology
Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Chapter 24, Problem 2AL

Vaccine development for diseases caused by protists (e.g., malaria, Chagas’ disease) has been much less successful than for bacterial or viral diseases. Discuss one biological reason and one geopolitical reason for this fact.

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A malaria vaccine has proved to be 77% effective in early trials and could be a major breakthrough against the disease, says the University of Oxford team behind it. Malaria kills more than 400,000 people a year, mostly children in sub-Saharan Africa. But despite many vaccines being trialled over the years, this is the first to meet the required target. The researchers say this vaccine could have a major public health impact. When trialled in 450 children in Burkina Faso, the vaccine was found to be safe, and showed "high-level efficacy" over 12 months of follow-up. Larger trials in nearly 5,000 children between the ages of five months and three years will now be carried out across four African countries to confirm the findings. Malaria is a life-threatening disease caused by parasites that are transmitted to people through mosquito bites. Although preventable and curable, the World Health Organization estimates there were 229 million cases worldwide in 2019 and 409,000 deaths.…
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