BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 24, Problem 1S
The FOX2 gene is associated with speech in human. It is also found in chimpanzees, gorillas, orangutans, rhesus macaques, and even the mouse, yet none of these mammals speak. Develop a hypothesis that explains whyFOXP2 supports speech in humans but not other mammals.
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The transcription factor Pax6 is required continually during the life of a mouse (or a human)
for the development of the retina. Homozygous Pax6 knockout mice die soon after birth
because Pax6 protein is also required in essential organs, such as the pancreas.
a) In order to study the role of Pax6 in eye development a researcher wants to
generate a mouse that expresses Pax6 everywhere except in its eyes. Describe
how you could construct such a mouse by floxing the gene. Is it possible to
achieve the same end with a transgene? (Hint: think about using cDNA and
RNAI)
b) Suppose you want to create a mouse similar to that in part (a), but one where the
eye cells from Pax6 function has been removed and now express a gene that
specifies a green fluorescent protein (GFP). Marking the cells in this way will
allow the investigators to see the shapes of the Pax6- eye cells more easily than
if they did not express GFP. Diagram a Pax6 gene construct that would enable
the researcher to do this…
Pax6 is a gene that is involved in mammalian eye development. Mutations in this gene result in a lack of iris in humans, and mice that are homozygous for the mutation lack eyes completely. Mutations in the eyeless gene in the fruitfly Drosophila result in reduced eyes. Expressing Pax6 from mammals in other tissues of Drosophila during its embryonic development can result in an ectopic eye (e.g. an eye expressed in a different tissue type). An example of an ectopic eye on the antenna of Drosophila is shown below.
Part A:
The eye of humans, mouse, and fly are an example of the following (check all that apply)
A. Structural analog
B. Structural homolog
C. Developmental homolog
D. Genetic homolog
Part B:
Darwin's hypothesis of natural selection has two components:
Species are not static but change through time
Species are related, and not independent.
In what ways does the human, mouse, and fly eye support or contradict one or both of the two components of…
The phenotype of a heterozygous mouse (Aa) is agouti. The agouti banding pattern is due to altered expression of the agouti gene. Which of the following statement is false?
a) Expression of the agouti gene inhibits the production of eumelanin.
b) Evidence suggests that the agouti gene is only expressed in tissues associated with fur production.
c) Epigenetic markers silence the agouti gene resulting in dark pigmentation at the tip and root of the hair.
d) All of the above
Chapter 24 Solutions
BIOLOGY
Ch. 24.1 - Prob. 1LOCh. 24.1 - Prob. 2LOCh. 24.1 - Prob. 3LOCh. 24.2 - Prob. 1LOCh. 24.2 - Prob. 2LOCh. 24.2 - Prob. 3LOCh. 24.2 - Explain why genome size and genome number do not...Ch. 24.3 - Define the terms segmental duplication, genome...Ch. 24.3 - Prob. 2LOCh. 24.4 - Prob. 1LO
Ch. 24.4 - Prob. 2LOCh. 24.5 - Prob. 1LOCh. 24.5 - Prob. 2LOCh. 24.5 - Prob. 3LOCh. 24 - Prob. 1DACh. 24 - Prob. 1IQCh. 24 - Prob. 2IQCh. 24 - Prob. 3IQCh. 24 - Humans and pufferfish diverged from a common...Ch. 24 - Prob. 2UCh. 24 - Prob. 3UCh. 24 - Homologous genes in distantly related organisms...Ch. 24 - All of the following are believed to contribute to...Ch. 24 - What is the fate of most duplicated genes? a. Gene...Ch. 24 - Chimp and human DNA whole-genome sequences differ...Ch. 24 - Prob. 2ACh. 24 - Analyze the conclusion that the Medicago...Ch. 24 - Analyze why an herbicide that targets the...Ch. 24 - The FOX2 gene is associated with speech in human....Ch. 24 - One of the common misconceptions about sequencing...Ch. 24 - How does horizontal gene transfer (HGT) complicate...
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