Chapter 19.7, Problem 14P

Interpretation Introduction

Interpretation:

The major product of the given reaction has to be given.

Concept Introduction:

Imidazoles are the aromatic compounds and also the heterocyclic ring of histidine. It exists in both protonated and non-protonated form at $\text{pH}=7.4$. Aromatic compounds such as benzene which is having closed ring and alternate double bonds undergo electrophilic aromatic substitution reactions. Electrophilic aromatic substitution takes place when an electrophile displaces a hydrogen atom of an aromatic ring.

There are five most common electrophilic aromatic substitution reactions that are halogenation, nitration, sulfonation, Friedel-Crafts acylation and Friedel-Crafts alkylation. All these reactions take place by same two-step mechanism.