Essential Organic Chemistry, Global Edition
Essential Organic Chemistry, Global Edition
3rd Edition
ISBN: 9781292089034
Author: Paula Yurkanis Bruice
Publisher: PEARSON
bartleby

Concept explainers

Question
Book Icon
Chapter 19, Problem 24P
Interpretation Introduction

Interpretation:

The mechanism for the synthesis of fatty acyl-CoA with the help of the enzyme Acyl-CoAsynthase has to be proposed.

Concept Introduction:

  Glycolysis: It is pathway which describes conversion of one molecule of glucose into two molecules of pyruvate. The series involves 10 reactions.

NAD+Molecule: It is the oxidized form of Nicotinamide adenine dinucleotide (NAD) which exists in all cells and needed for activation of enzymes.

NADHmolecule: It is coenzyme which gets oxidized on reducing another compound. The oxidized form of NADHisNAD+.

Fatty acid conversion to fatty acyl-CoA: Many steps are involved in the catabolism of fats in our body.  A fatty acid formed can be converted into fatty acyl-CoA in the presence of an enzyme called Acyl-CoAsynthase.  The fatty acid should be activated before it can be metabolized.

Blurred answer
Students have asked these similar questions
The rate-limiting step is a metabolic pathway is the slowest step which determines the overall rate of the other reactions in the pathway. In glycolysis, the rate limiting step is a phosphorylation reaction where phosphofructokinase (PFK-1) catalyzes the reaction fructose-6-bisphosphate -> fructose-1,6-bisphosphate, the same step in gluconeogenesis. Select one: The statement is FALSE. The statement is TRUE.
4. Liver alcohol dehydrogenase (LADH) catalyzes a reversible, pH-dependent oxidation of an alcohol to an aldehyde according to the following reaction: LADH RCH2OH + NAD* RCHO + NADH + H* where NAD* and NADH are, respectively, the oxidized and reduced forms of the cofactor nicotin-amide adenine dinucleotide. While the reaction is actually a two-substrate reaction, it proceeds like a one- substrate reaction through a so-called compulsory-ordered ternary complex mechanism. It has been shown through kinetic studies that, in the case of primary alcohols, the enzyme binds first the cofactor forming a binary enzyme-NAD* complex that then binds the second substrate, the alcohol, to form a ternary enzyme-NAD*-substrate complex in which the oxidation of the alcohol proceeds with reduction of the cofactor. While the enzyme catalyzes oxidation of various steroids as well as ingested ethanol, it also catalyzes the oxidation of methanol CH3OH, forming the extremely toxic product formaldehyde HCHO.…
Cholesterol-lowering drugs commonly target O HMG-COA synthase, the enzyme that catalyzes the synthesis of mevalonate O pyruvate decarboxylase complex, which catalyzes the synthesis of acetyl-CoA O mevalonate, an isoprene O HMG-COAreductase, the rate-limiting enzyme in cholesterol biosynthesis O HMG-CoA synthase, the enzyme that catalyzes the first step in cholesterol biosynthesis
Knowledge Booster
Background pattern image
Chemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
Text book image
Organic And Biological Chemistry
Chemistry
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:Cengage Learning,
Text book image
General, Organic, and Biological Chemistry
Chemistry
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:Cengage Learning
Text book image
Pushing Electrons
Chemistry
ISBN:9781133951889
Author:Weeks, Daniel P.
Publisher:Cengage Learning
Text book image
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning