Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 17, Problem 9P
Interpretation Introduction
Interpretation:
Explain the advantages of compartmentalization of particular
Introduction:
Compartmentalization helps to takes place in two opposing pathways in two separate places. This also provides favorable conditions to certain reactions.
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Which out of the following statements is true about the regulation of metabolic pathway?
a) Most of the metabolic pathways are regulated
b) Most of the metabolic pathways are not regulated
c) Regulation of metabolic pathways always involves changing the amount of enzymes
d) Metabolic regulation always depends on control by hormones
What is metabolic coupling?
In the metabolic pathway, A->B->C->D->E what effect would molecule E likely have on the enzyme that catalyzes A->B? (The answer is A. Could you justify the reason why the answer is A?)
a) Allosteric inhibitor
b)Allosteric activator
c) Competitive inhibitor
d) feedback activator
e) coenzyme
Chapter 17 Solutions
Biochemistry
Ch. 17 - Global Carbon Dioxide Cycling Expressed as Human...Ch. 17 - Prob. 2PCh. 17 - Where Do the O Atoms in Organisms Come From? Name...Ch. 17 - How Do Catabolism and Anabolism Differ? What are...Ch. 17 - How Art the Enzymes of Metabolic Pathways...Ch. 17 - Why Do Anabolic and Catabolic Pathways Differ? Why...Ch. 17 - Prob. 7PCh. 17 - How Is Metabolism Regulated? (Integrates with...Ch. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Which Is “Better: NMR or MS? Compare and...Ch. 17 - How Do Vitamin-Derived Coenzymes Aid Metabolism?...Ch. 17 - What Art the Features of the Series of -omes?...Ch. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Which of the following experimental approaches is...Ch. 17 - Prob. 20P
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- Metabolic pathways can function efficiently without external control, and will not overproduce unnecessary product molecules because: a) Large pH shifts speed up reactions b) Cells release lots of heat to accelerate product formation c) End products of a pathway cause early enzymes to change shape and inactivate d) Active sites become saturated as product concentration risesarrow_forwardWhy must metabolic pathways be regulated? Cite three ways by which metabolic pathways are regulated.arrow_forwardWhich of the following are common to all metabolic pathways? a) Citric acid cycle b) Oxidative phosphorylation c) Electron transport chain d) All of the abovearrow_forward
- Explain the role that compartmentation plays in theregulation of metabolic pathways. Provide severalexamples.arrow_forwardHow is a “committed step” defined in the context of a metabolic pathway and why are they important? Which steps and/or enzymes are involved in the committed steps in the Krebs Cycle? What are the possible implications of these steps were deregulated?arrow_forwardDefine the terms metabolic channeling and compartmentation. How are they involved in the regulation of metabolism?arrow_forward
- There are many metabolic pathways in a biological system, and it is critical to regulate these pathways so that only particular pathways are active at a single time. Which enzyme would be in the regulation point in the hypothetical pathway shown below. A¹B 2C 3 D4E A) A → B B) B-C C) C-D D) D→ E E) The regulation point is highly dependent upon the metabolic pathway.arrow_forwardwhat metabolic pathways are more likely to be active during: a) fasting, b) overnight fast) and c) fed state?arrow_forwardWhat is the significance of metabolic flux?arrow_forward
- The enzyme Phosphofructokinase (PFK) is a key regulator of glycolysis. A) Does ATP bind the PFK allosteric siteor the active site? B) Does high amount of ATP in the cell activate or inhibit PFK? Why? C)What do you suppose happens to glucose if glycolysis is inhibited in the cell?arrow_forwardWhat is the total output of ATP, aerobically, in prokaryotic cells and eukaryotic cells?arrow_forwardQ: Select the features of the structure and functioning of allosteric enzymes: a) are metabolic pathway limiting enzymes b) when interacting with ligands do not show a cooperative effect c) are monomeric proteins d) have spatially separated active and regulatory centers e) do not exhibit regulatory properties during dissociation of the molecule into protomersarrow_forward
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